SynthesisBMC anesthesiology2025
Intraoperative hypotension and postoperative risks in non-cardiac surgery: a meta-analysis.
Synthesis in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical performance of machine-learning algorithms to predict intraoperative hypotension: a meta-analysis.BMC surgery · 2025Pooled it
- HOPFIT: A neuro-cardiovascular monitoring framework for precision sedation, anaesthesia, and resuscitation.Journal of clinical monitoring and computing · 2026Review
- Intraoperative blood pressure strategies and neurocognitive outcomes: A systematic review.Journal of anesthesia and translational medicine · 2026Review
- Transformer-based deep learning model for real-time prediction of intraoperative hypotension using dynamic time-series vital signs: A retrospective study.PLoS medicine · 2026Article
- Intraoperative Hypotension and Vasoactive Treatment: An International Survey of Anaesthesiologists.Acta anaesthesiologica Scandinavica · 2026Article
- Exposure-based stratification of postoperative complications in major cardiac surgical procedures: a retrospective cohort study using the MOVER database.Frontiers in cardiovascular medicine · 2026Article
- Intraoperative Hypotension and Delayed Graft Function after Kidney Transplantation: A Retrospective Cohort Analysis.Anesthesiology open · 2026Article
- Development of a machine learning algorithm model to predict intraoperative hypotension in elderly patients undergoing thoracic and abdominal surgeries.Open medicine (Warsaw, Poland) · 2026Article
- Preoperative TAPSE/PASP Ratio as a Non-Invasive Predictor of Hypotension After General Anesthesia Induction.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPostoperative complications are often associated with the severity and duration of intraoperative hypotension. However, the optimal approach for managing intraoperative hypotension remains controversial. The aim of this meta-analysis of randomized controlled trials was to compare the incidence of common postoperative complications with different treatment threshold of hypotension.
methodsWe searched PubMed, the Cochrane Database, and Embase from August 2014 to August 2024 for studies comparing different treatment threshold of hypotension (low [mean arterial pressure < 60 mmHg], moderate [60-75 mmHg], and high [> 75 mmHg]). Only randomized controlled trials conducted during 2014-2024 were included in this meta-analysis without language restrictions. Studies with the following characteristics were included: randomized controlled study; involved non-cardiac, non-obstetric surgery; included different blood pressure management strategies; evaluated major postoperative complications; and included acute kidney injury, myocardial injury, altered consciousness, or infection. Data included patient age, type of surgery, group criteria, and adverse events. Mantel-Haenszel method was used for analysis. The primary outcomes were postoperative complications, including acute kidney injury. The secondary outcomes included length of hospital stay and all-cause mortality.
resultsOf the 2160 studies identified, eight randomized controlled trials with 9108 participants were included. No significant differences in postoperative complications were observed between the moderate and high mean arterial pressure treatment threshold groups (risk ratio = 1.0, 95% confidence interval = 0.86-1.18, P = 0.96). Sensitivity analysis confirmed these findings. Length of hospitalization was not significantly different between the groups (standardized mean difference = -0.39; 95% confidence interval = -0.69 to 1.31; P = 0.03). Limited data prevented meta-analysis of mean arterial pressure management at lower treatment thresholds.
conclusionThe results of this meta-analysis suggest no significant differences in postoperative complications between moderate and high mean arterial pressure management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.