ArticleNature2025
Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
0numbers the graph read from it
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36citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed.
- Probiotic extracellular vesicles reprogram macrophage immunometabolism: From gut crosstalk to host health.Gut microbes · 2026Review
- Ternary mTOR-targeted conductive nanofibrous scaffolds with bioactive peptides orchestrate immune-metabolic-fibrotic balance for diabetic bone regeneration.Bioactive materials · 2026Article
- Regulating xenophagy and phenotype of macrophages by selenium-doped nanoleaves on Zn-based implants for infected bone integration.Bioactive materials · 2026Article
- Programmable-bacteria-macrophage backpacks for enhanced solid tumor therapy via mechanobiological interplay.Cell reports. Medicine · 2026Article
- Preservation of Antioxidant and Immunomodulatory Properties in a Heat-Treated Probiotic Blend: Insights from Preclinical Models.Microorganisms · 2026Article
- Hydrophilic-Stable Nucleoside-Based Hydrogen-Bonded Organic Frameworks (N-HOF) for Therapeutic Bacterial Hybrid Systems.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Bacterial surface display enables lysis-independent joint host-pathogen single-cell profiling.bioRxiv : the preprint server for biology · 2026Article
- From tumor targeting to tumor accessibility: surface-engineered bacteria as precision living therapeutics for translational medicine.Journal of hematology & oncology · 2026Review
- "Artificial platelet injection system": a plug-and-play platelet-based lysosome-targeting chimera for targeted protein degradation.Bioactive materials · 2026Article
- Copper Metabolism in Isolated Macrophages: Regulator of Immunity and Inflammation.Veterinary sciences · 2026Review
- Dynamic collaboration between mitochondria and organelles: mechanisms, functions, and disease implications.Apoptosis : an international journal on programmed cell death · 2026Review
- Phagocytosis: a process that shapes immune responses to engulfed meals.Nature reviews. Immunology · 2026Review
- Neutrophil Activation Decreases Ability to Kill Oral Streptococcus gordonii.Molecular oral microbiology · 2026Article
- T6SS mutants exploit itaconate to support infection of phagocytes.bioRxiv : the preprint server for biology · 2026Article
- Iron, arginine, and redox metabolism in peripheral blood mononuclear cells distinguishes sickle cell disease and pulmonary hypertension.HemaSphere · 2026Article
- Modulation of immune cells and metabolic reprogramming in efferocytosis.Cell death & disease · 2026Review
- Progranulin impairs efferocytosis of macrophages in renal fibrosis by negatively regulating PPAR-δ-mediated inhibition of the JAK-STAT signaling pathway.Cellular and molecular life sciences : CMLS · 2026Article
- Intratumoral immune-microbial crosstalk shaped by tumor cell-derived extracellular vesicles encapsulating berberine boosts lung cancer immunotherapy.Acta pharmaceutica Sinica. B · 2026Article
- Methicillin-resistant and susceptible Staphylococcus aureus: tolerance, immune evasion and treatment.Nature reviews. Microbiology · 2026Review
- Glycolytic reprogramming and immune responses in macrophages: a crosstalk driven by bacterial infection.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Juliette LesbatsUniversity of Bordeaux, INSERM, MRGM, U1211, Bordeaux, France.
Aurélia BrillacUniversity of Bordeaux, INSERM, MRGM, U1211, Bordeaux, France.
Julie A Reisz *Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Parnika Mukherjee *Department of Infectious Diseases, Respiratory Medicine, and Critical Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-5365-9541
Charlène LhuissierImmunoConcEpT, CNRS UMR 5164, INSERM ERL 1303, University of Bordeaux, Bordeaux, France.
Mónica Fernández-MonrealUniversité de Bordeaux, CNRS, INSERM, Bordeaux Imaging Center (BIC), Bordeaux, France.ORCID 0000-0001-7278-448X
Jean-William DupuyUniversity of Bordeaux, CNRS, INSERM, TBM-Core, US5, UAR3421, OncoProt, Bordeaux, France.ORCID 0000-0002-2448-4797
Angèle SequeiraImmunoConcEpT, CNRS UMR 5164, INSERM ERL 1303, University of Bordeaux, Bordeaux, France.
Gaia TioliUniversity of Bordeaux, INSERM, MRGM, U1211, Bordeaux, France.ORCID 0000-0002-5405-9150
Celia De La Calle ArreguiMetabolism and Cell Signalling Laboratory, Spanish National Cancer Research Center (CNIO), Madrid, Spain.ORCID 0000-0002-4627-2963
Benoît PinsonService Analyses Métabolomiques, TBMCore, CNRS UAR 3427, INSERM US005, Université Bordeaux, Bordeaux, France.ORCID 0000-0003-2936-9058
Daniel WendischDepartment of Infectious Diseases, Respiratory Medicine, and Critical Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0003-1968-5751
Benoît RousseauUniversity of Bordeaux, Animal Facility A2, Service Commun des Animaleries, Bordeaux, France.
Alejo EfeyanMetabolism and Cell Signalling Laboratory, Spanish National Cancer Research Center (CNIO), Madrid, Spain.ORCID 0000-0002-3806-6799
Leif Erik SanderDepartment of Infectious Diseases, Respiratory Medicine, and Critical Care, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-0476-9947
Angelo D'AlessandroDepartment of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID 0000-0002-2258-6490
Johan GaraudeUniversity of Bordeaux, INSERM, MRGM, U1211, Bordeaux, France. johan.garaude@inserm.fr.ORCID 0000-0001-7789-7715
Funding
French Ministry of Research and the University of Bordeauxthe University of Bordeaux
Abstract
Macrophages specialize in phagocytosis, a cellular process that eliminates extracellular matter, including microorganisms, through internalization and degradation
Indexed as
BacteriaEnergy MetabolismMacrophagesPhagocytosisAmino AcidsAMP-Activated Protein KinasesAnimalsCyclic AMPFemaleGlutathioneInterleukin-1betaMaleMechanistic Target of Rapamycin Complex 1MiceMice, Inbred C57BLMicrobial ViabilityAmino AcidsAMP-Activated Protein KinasesCyclic AMPGlutathioneInterleukin-1betaitaconic acidMechanistic Target of Rapamycin Complex 1Reactive Oxygen SpeciesSuccinates
Identifiers
PMID
40011782What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.