Evidence map›Paper›PMID 40011746›Full record

ArticleNature structural & molecular biology2025

Structure of the human K

Shatabdi Roy-Chowdhury, Seil Jang, Fayal Abderemane-Ali, Fiona Naughton, Michael Grabe, Daniel L Minor

Erratum issuedAbstract read
In one paragraph

Article in Nature structural & molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Hydrophobic mismatch induces lipid sorting based on tail unsaturation.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Shatabdi Roy-ChowdhuryCardiovascular Research Institute, UCSF Medical Center, San Francisco, CA, USA.
Seil JangCardiovascular Research Institute, UCSF Medical Center, San Francisco, CA, USA.
Fayal Abderemane-AliCardiovascular Research Institute, UCSF Medical Center, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-7097-1684
Fiona NaughtonCardiovascular Research Institute, UCSF Medical Center, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-0162-1346
Michael GrabeCardiovascular Research Institute, UCSF Medical Center, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-3509-5997
Daniel L MinorCardiovascular Research Institute, UCSF Medical Center, San Francisco, CA, USA. daniel.minor@ucsf.edu.ORCID http://orcid.org/0000-0002-5998-4214

Funding

Genetic and chemical biological studies of K2P structure, function, andmodulationR01MH093603 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DANIEL L MINOR · 2011 to 2026
$8.5M
Glacios™ Cryo Transmission Electron Microscope with 200 kV XFEG opticsS10OD026881 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHENG, YIFAN · 2019 to 2019
$1.8M
NIH HHS S10 OD026881NIMH NIH HHS R01 MH093603
6 · The paper itself

Abstract

Polyunsaturated fatty acid (PUFA) lipids modulate the neuronal and microglial leak potassium channel K

Indexed as

Fatty Acids, UnsaturatedPotassium ChannelsBinding SitesCryoelectron MicroscopyHumansHydrophobic and Hydrophilic InteractionsIon Channel GatingModels, MolecularProtein ConformationFatty Acids, UnsaturatedPotassium Channels

Identifiers

PMID40011746
PMCPMC13061574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.