Evidence map›Paper›PMID 40011741›Full record

ArticleEye (London, England)2025

Sleep and mood in central serous chorioretinopathy.

Yunfei Yang, Victoria S Foster, Sophie Marlowe, Sarah R Stevenson, Iona Alexander, SOMNUS Study Group, Russell G Foster, Susan M Downes

Abstract read
In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yunfei Yang *Department of Ophthalmology, Lister Hospital, East and North Hertfordshire NHS Foundation Trust, Coreys Mill Ln, Stevenage, SG1 4AB, England.ORCID http://orcid.org/0000-0002-7130-9801
Victoria S Foster *Oxford Eye Hospital, West Wing, Oxford University Hospitals Foundation Trust, Headington, Oxford, OX3 9DU, England.ORCID http://orcid.org/0000-0001-9991-5451
Sophie MarloweGreat Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, UK.
Sarah R StevensonOphthalmology Department of the Royal Gwent Hospital, Cardiff Road, Newport, NP20 2UB, UK.
Iona AlexanderOxford Eye Hospital, West Wing, Oxford University Hospitals Foundation Trust, Headington, Oxford, OX3 9DU, England.
SOMNUS Study Group
Russell G FosterSir Jules Thorn Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, Dorothy Crowfoot Hodgkin Building, University of Oxford, South Parks Road, Oxford, OX1 3QU, England. russell.foster@eye.ox.ac.uk.
Susan M DownesOxford Eye Hospital, West Wing, Oxford University Hospitals Foundation Trust, Headington, Oxford, OX3 9DU, England. susan.downes@eye.ox.ac.uk.

Funding

Wellcome TrustWellcome Trust (Wellcome) 106174/Z/14/Z
6 · The paper itself

Abstract

purposeTo investigate the impact of central serous chorioretinopathy on sleep and mood in patients with acute and chronic central serous chorioretinopathy.

methodsThis cross-sectional study compared sleep and mood differences between central serous chorioretinopathy and control patients recruited from Ophthalmology clinics at the John Radcliffe Hospital, Oxford between 2012 and 2020. Data including visual acuity, type of central serous chorioretinopathy (acute or chronic; aCSC/cCSC), sex, and chronotype were obtained. Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI); the Hospital Anxiety and Depression Scale (HADS) was used to evaluate anxiety (HADS-A) and depression (HADS-D).

resultsA total of 247 age matched controls and 109 patients with central serous chorioretinopathy participated. There were no significant differences in PSQI or HADs (P > 0.05) between the two groups. Females exhibited significantly higher PSQI scores than males both for control and central serous chorioretinopathy groups (P < 0.05). Within the central serous chorioretinopathy group, 88 (81%) had chronic central serous chorioretinopathy and 21 (19%) had acute central serous chorioretinopathy, and an increase in daytime dysfunction was seen in the acute phenotype compared to chronic (P = 0.018).

conclusionIn our study, no significant differences in sleep quality or mood scores were identified in central serous chorioretinopathy patients, when compared to controls. Worsened sleep for females was present when compared to males, both in central serous chorioretinopathy and control groups. Within central serous chorioretinopathy groups, worsened daytime function was observed in acute versus chronic - a larger study would help distinguish the effect of chronicity on sleep.

Indexed as

AffectCentral Serous ChorioretinopathySleepSleep QualityAdultChronic DiseaseCross-Sectional StudiesFemaleHumansMaleMiddle AgedVisual Acuity

Identifiers

PMID40011741
PMCPMC12089360

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.