Evidence map›Paper›PMID 40011687›Full record

Trial reportScientific reports2025

Effects of 12-week whole-body vibration training versus resistance training in older people with sarcopenia.

Min Zhuang, Yifan Gu, Zhou Wang, Xiangfeng He, Nan Chen

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  17. Nutrition and exercise for sarcopenia treatment.Osteoporosis and sarcopenia · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min Zhuang *Department of Rehabilitation, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Yifan Gu *Department of Rehabilitation, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Zhou Wang *Department of Rehabilitation, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Xiangfeng HeDepartment of Rehabilitation, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China.
Nan ChenDepartment of Rehabilitation, Chongming Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China. chennanreh2020@126.com.

Funding

the Center for Whole Population Whole Lifecycle Cohort Clinical Research 22MC2022001the project of National Natural Science Foundation of China "Mechanism of the Regulation of Skeletal Muscle Cell AMPK Pathway by Intestinal P.merdae in the Progression of Sarcopenia 82102651
6 · The paper itself

Abstract

Sarcopenia is a syndrome commonly found in older people. The aim of this study was to evaluate the effects of whole-body vibration training (WBVT) and resistance training (RT) on body composition, muscle strength, physical performance and blood biomarkers in older people with sarcopenia. We conducted a 12-week, 3-times-weekly assessor-blinded, randomized controlled trial of 27 older people with sarcopenia aged ≥ 65 years. Subjects were randomized into WBVT group (n = 14) and RT group (n = 13). The primary outcome was knee extension strength (KES). Secondary outcomes were body composition [body weight, body mass index (BMI), percentage of body fat (PBF), and appendicular skeletal muscle mass index (ASMI)], muscle strength [handgrip strength (HS)], physical performance [gait speed (GS), 5-time chair stand test (5CST), and short physical performance battery (SPPB)], blood biomarkers (inflammatory factors, hormones, growth factors, and muscle injury biomarker), and quality of life questionnaire [medical outcomes study short-form 36 (SF-36)]. After 12-week intervention, in the WBVT group, we observed significant improvements in body composition (weight, BMI, PBF and ASMI), muscle strength (KES), physical performance (GS, SPPB and 5CST), blood biomarkers [insulin-like growth factor 1 (IGF-1), growth hormone, follistatin (FST) and creatine kinase (CK)] and quality of life. In the RT group, we observed significant improvements in body composition (weight, BMI and PBF), muscle strength (KES), physical performance (GS and SPPB), blood biomarkers (growth hormone, FST and CK) and quality of life. Between-group comparisons were only significant for KES (P = 0.007) and the role-physical (RP) dimension of the SF-36 (P = 0.007). WBVT and RT both improved the physical condition of older people with sarcopenia. RT excelled in muscle strength, but WBVT offered an alternative for those with restrictions. WBVT's low risk and flexibility suited diverse conditions, providing a new rehabilitation option for patients with sarcopenia.

Indexed as

Resistance TrainingSarcopeniaVibrationAgedAged, 80 and overBiomarkersBody CompositionBody Mass IndexFemaleHand StrengthHumansMaleMuscle, SkeletalMuscle StrengthPhysical Functional PerformanceQuality of LifeBiomarkersResistance trainingSarcopeniaWhole-body vibration training

Identifiers

PMID40011687
PMCPMC11865505

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.