Evidence map›Paper›PMID 40011487›Full record

ArticleScientific reports2025

Mycoplasma pneumoniae MLST detected in the upsurge of pneumonia during the 2023 to 2024 winter season in the Netherlands.

Pieter W Smit, Dirk Eggink, Sunita Paltansing, Mariette Hooiveld, Arianne B van Gageldonk-Lafeber, Djoo Dunk, Sybren Lekkerkerk, Adam Meijer

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Global molecular epidemiology ofEmerging microbes & infections · 2026
    Pooled it
  2. Post-pandemic surge ofJournal of clinical microbiology · 2026
    Article
  3. Article
  4. Article
  5. The value of serum CARDS toxin and NETs formation in children with MPP.Frontiers in cellular and infection microbiology · 2026
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pieter W SmitMaasstad Hospital, Rotterdam, The Netherlands. SmitP@maasstadziekenhuis.nl.
Dirk EgginkCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Sunita PaltansingFranciscus Gasthuis and Vlietland Hospital, Rotterdam, The Netherlands.
Mariette HooiveldNivel, Utrecht, The Netherlands.
Arianne B van Gageldonk-LafeberCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Djoo DunkMaasstad Hospital, Rotterdam, The Netherlands.
Sybren LekkerkerkMaasstad Hospital, Rotterdam, The Netherlands.
Adam MeijerCentre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the winter 2023-2024, an upsurge of Mycoplasma pneumoniae (M.pneumoniae) was noted in the Netherlands. To investigate the distribution of M.pneumoniae sequence types from different patient populations and to explore genotypic macrolide resistance which is common in East Asia but not (yet) in Europe. M.pneumoniae positive throat/nasal samples from participatory respiratory surveillance, patients visiting general practitioners with an acute respiratory infection including community acquired pneumonia (CAP) and hospitalised patients with CAP were included, representing different disease severity. The M.pneumoniae were typed with multilocus sequence typing and the 23 S rRNA region was sequenced to determine macrolide resistance markers. In total, 153 M.pneumoniae were sequenced, six sequence types (STs) and only one bacterium with macrolide resistance marker were detected. No link between STs or bacterial load (PCR cycle threshold) and source population of M.pneumoniae was detected. In the Netherlands, the M.pneumoniae upsurge in 2023-2024 existed of multiple commonly found STs. No link between ST and severity of illness was detected. Macrolide resistance remained sporadic.

Indexed as

Mycoplasma pneumoniaePneumonia, MycoplasmaAdolescentAdultAgedAnti-Bacterial AgentsChildChild, PreschoolCommunity-Acquired InfectionsDrug Resistance, BacterialFemaleHumansMacrolidesMaleMiddle AgedMultilocus Sequence TypingAnti-Bacterial AgentsMacrolidesRNA, Ribosomal, 23SCAPCommunityGeneral practitionerHospitalMLST typesMycoplasma pneumoniaeOther acute respiratory illnessResistance

Identifiers

PMID40011487
PMCPMC11865550

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.