Evidence map›Paper›PMID 40011359›Full record

ArticleMolecular neurobiology2025

Adenine Nucleotide Translocase 1 Promotes Functional Integrity of Mitochondria via Activating DDIT3-CytC Pathway and Intensifying Actin Filament Structures.

Jun Liu, Wenyong Ding, Qianhui Chen, Yuanwen Peng, Ying Kong, Li Ma, Wenli Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun Liu *Department of Epidemiology, Dalian Medical University, Dalian, 116044, China.
Wenyong DingBiochemistry and Molecular Biology Department of College of Basic Medical Sciences, Dalian Medical University, Dalian, 116044, China.
Qianhui Chen *Biochemistry and Molecular Biology Department of College of Basic Medical Sciences, Dalian Medical University, Dalian, 116044, China.
Yuanwen PengDepartment of Epidemiology, Dalian Medical University, Dalian, 116044, China.
Ying KongBiochemistry and Molecular Biology Department of College of Basic Medical Sciences, Dalian Medical University, Dalian, 116044, China.
Li MaDepartment of Epidemiology, Dalian Medical University, Dalian, 116044, China. mali_lele@sina.com.
Wenli ZhangBiochemistry and Molecular Biology Department of College of Basic Medical Sciences, Dalian Medical University, Dalian, 116044, China. zhangwenli@dmu.edu.cn.ORCID http://orcid.org/0000-0002-2373-1709

Funding

Applied Basic Research Project of Liaoning Province 2022JH2/101300084
6 · The paper itself

Abstract

Adenine nucleotide translocase 1 (ANT1), involved in exchanging ATP and ADP across the mitochondrial inner membrane, is downregulated in mouse brains with Parkinsonian variations. To further explore the role of ANT1 in neuronal cells, an intensive investigation was conducted by introducing overexpressed ANT1 and ANT1 mutant at Asn177 into neuroblastoma SH-SY5Y cells treated with MPP

Indexed as

Actin CytoskeletonAdenine Nucleotide Translocator 1MitochondriaSignal TransductionApoptosisCell Line, TumorHumansMembrane Potential, MitochondrialReactive Oxygen SpeciesAdenine Nucleotide Translocator 1Reactive Oxygen SpeciesAdenine nucleotide translocase 1CytCDDIT3MitochondriaParkinson’s diseaseRNA-Seq

Identifiers

PMID40011359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.