SynthesisBehavior research methods2025
Approaches to inducing mental fatigue: A systematic review and meta-analysis of (neuro)physiologic indices.
Synthesis in Behavior research methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Mental fatigue and brain activation using prolonged task-based fMRI: a systematic review on time-on-task and sequential task paradigms.Experimental brain research · 2026Pooled it
- The effects of brain endurance training on physical endurance performance under mental fatigue and non-fatigued conditions: a systematic review and meta-analysis.Frontiers in psychology · 2026Pooled it
- The effects of brain endurance training on mental fatigue, endurance, and cognitive function: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Design and Experimental Investigation of a Multi-Level Heartbeat Sound Feedback-Based Neurofeedback System: Neural Mechanisms.Sensors (Basel, Switzerland) · 2026Article
- Comparative Prefrontal Multimodal Physiological Signatures Under Active- and Passive-Fatigue-Inducing Simulated Driving Paradigms.Brain sciences · 2026Article
- Short video addiction is associated with students' academic disengagement: a moderated mediation analysis.Scientific reports · 2026Article
- Assessing mental fatigue in football: a systematic review.Frontiers in sports and active living · 2026Review
- Classical back massage is associated with lower heart rate and sustained mean skin conductance during recovery after cognitive load: an exploratory controlled pilot study.Frontiers in physiology · 2026Article
- A dual-branch multidimensional attention fusion network for EEG-based fatigue classification.Frontiers in physiology · 2026Article
- Operational drift: why validated fatigue induction is the missing link in nature restoration research.Frontiers in psychology · 2026Article
- EEG-based monitoring of mental fatigue during virtual-reality motor imagery tasks.Frontiers in behavioral neuroscience · 2026Article
- Current Practices for Mental Fatigue Quantification and Induction in Movement Science: Introducing the SPeCIFY Guidelines.Sports medicine (Auckland, N.Z.) · 2025Review
- Impact of mental fatigue on lower limb biomechanics and non-contact anterior cruciate ligament injury risk in basketball players during the stop-jump task: a self-controlled trial.Journal of orthopaedic surgery and research · 2025Article
- The Differential and Interactive Effects of Aging and Mental Fatigue on Alpha Oscillations: A Resting-State Electroencephalography Study.Brain sciences · 2025Article
- Investigating the isolated effects of a soccer-specific mental fatigue manipulation on different task types.Frontiers in psychology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mental fatigue is a transient psychophysiological state characterized by impaired cognition and behavior across a range of dynamic contexts. Despite increasing interest in this phenomenon, its (neuro)physiologic representations remain unclear. This systematic review aimed to quantify the range of (neuro)physiologic outcomes and methodologies used to investigate mental fatigue in laboratory-based settings. Across the 72 studies meeting our inclusion criteria, we identified 30 unique physiologic, four visual outcomes, and the application of several neuroimaging techniques investigating neuronal function. Mental fatigue increased heart rate, systolic and diastolic blood pressure, mean arterial pressure, low frequency, and root mean square of successive differences (RMSSD), and reduced standard deviation of normal-to-normal intervals (SDNN) (all P ≤ 0.04) when compared with controls. Applying electroencephalography to investigate delta, theta, and alpha bandwidths may provide useful insights into this phenomenon, and functional near-infra-red spectroscopy to right-lateralized frontoparietal regions would be helpful to investigate cortical activity change in response to mental fatigue. More data are needed across a range of methodological contexts in order to further determine the (neuro)physiological manifestations of mental fatigue. However, this review provides direction to researchers and will assist them in navigating and considering the range of options available.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.