ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025
A Shift Toward Supercritical Brain Dynamics Predicts Alzheimer's Disease Progression.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From Single-Modal to Multi-Modal Artificial Intelligence in Alzheimer's Disease: A Systematic Review of Databases, Modalities, Diagnostic Performance, and Clinical Translation Challenges.Sensors (Basel, Switzerland) · 2026Pooled it
- Clinical markers of disease progression in the prodromal to overt alpha-synucleinopathy continuum.Brain : a journal of neurology · 2026Article
- Altered Scale-Free Dynamics of Spontaneous Brain Activity in Post-Traumatic Stress Disorder: Relationship to Impaired Functional Connectivity.Brain sciences · 2026Article
- Multiscale metabolic covariance networks uncover stage-specific biomarker signatures across the Alzheimer's disease continuum.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- AI-driven magnetoencephalography biomarkers in dementia risk prediction: current evidence, challenges and future perspectives.Frontiers in dementia · 2026Review
- Toward precision neuroscience in Alzheimer's disease: the role of multimodal AI.Frontiers in aging neuroscience · 2026Review
- From visibility graphs to cognition.Frontiers in network physiology · 2026Article
- Abnormally enhanced temporal correlations of alpha oscillations across multiple timescales in tinnitus patients.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Unveiling Cortical Criticality Changes along the Prodromal to the Overt Continuum of Alpha-Synucleinopathy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Genetic contributions to brain criticality and its relationship with human cognitive functions.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Altered intrinsic ignition dynamics linked to Amyloid-bioRxiv : the preprint server for biology · 2025Article
- Critical dynamics predicts cognitive performance and provides a common framework for heterogeneous mechanisms impacting cognition.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Local gyrification index and sulcal depth as imaging markers of cognitive decline in Alzheimer's disease.Frontiers in aging neuroscience · 2025Article
- Hippocampal and cortical activities reflect early hyperexcitability in an Alzheimer's mouse model.Brain communications · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is the most common form of dementia with continuum of disease progression of increasing severity from subjective cognitive decline (SCD) to mild cognitive impairment (MCI) and lastly to AD. The transition from MCI to AD has been linked to brain hypersynchronization, but the underlying mechanisms leading to this are unknown. Here, we hypothesized that excessive excitation in AD disease progression would shift brain dynamics toward supercriticality across an extended regime of critical-like dynamics. In this framework, healthy brain activity during aging preserves operation at near the critical phase transition at balanced excitation-inhibition (E/I). To test this hypothesis, we used source-reconstructed resting-state MEG data from a cross-sectional cohort (
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