Evidence map›Paper›PMID 40010976›Full record

ReviewIn vivo (Athens, Greece)

Pancreatic Mixed Acinar-neuroendocrine Carcinoma in a Patient With a Germline

Yosuke Saito, Shuhei Suzuki, Tomomi Sanomachi, Kaho Kato, Hiroya Otake, Yuko Nishise, Yuta Yamada, Koki Saito, Koshi Takahashi, Ryosuke Kumanishi and 2 more

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yosuke SaitoDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan.
Shuhei SuzukiDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan; s-suzuki@med.id.yamagata-u.ac.jp.
Tomomi SanomachiDepartment of Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
Kaho KatoMaster of Public Health, Human Genetics, University of Pittsburgh, Pittsburgh, PA, U.S.A.
Hiroya OtakeDepartment of Pathology, Yamagata City Hospital Saiseikan, Yamagata, Japan.
Yuko NishiseDepartment of Gastroenterology, Yamagata City Hospital Saiseikan, Yamagata, Japan.
Yuta YamadaDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan.
Koki SaitoTokyo Medical University, Tokyo, Japan.
Koshi TakahashiDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan.
Ryosuke KumanishiDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan.
Tadahisa FukuiDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan.
Takashi YoshiokaDepartment of Clinical Oncology, Yamagata University Hospital, Yamagata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimCowden syndrome (CS)/PTEN hamartoma tumor syndrome (PHTS) is a hereditary disorder caused by germline CASE REPORT: A male in his late 40s presented with pancreatic cancer and hepatic metastases. His medical history included thyroid cancer and familial gastrointestinal malignancies. Liver biopsy revealed mixed acinar-endocrine carcinoma. Cancer genome profiling identified pathogenic variants in

conclusionThis case highlights a rare presentation of pancreatic cancer in CS/PHTS with distinct molecular and histological features. The absence of

Indexed as

Carcinoma, Acinar CellCarcinoma, NeuroendocrineGerm-Line MutationHamartoma Syndrome, MultiplePancreatic NeoplasmsPTEN PhosphohydrolaseAdultAntineoplastic Combined Chemotherapy ProtocolsGenomicsHumansMalePTEN PhosphohydrolasePTEN protein, humanCowden syndromegenome profiling testinggermline variantpancreatic cancerPTEN

Identifiers

PMID40010976
PMCPMC11884457

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.