Evidence map›Paper›PMID 40010965›Full record

ReviewIn vivo (Athens, Greece)

Chronic Kidney Disease Following Cardiac Arrest Manifesting as Dyspnoea and Peripheral Oedema in Cardiovascular Multimorbidity: Case Analysis and Brief Literature Review.

Kira Harding, Kate Emblin, Anca Ichim, Daniel Adlington, Rob Daniels, Kinan Mokbel

Abstract readCase ReportsReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kira HardingDepartment of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.
Kate EmblinDepartment of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.
Anca IchimDepartment of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.
Daniel AdlingtonUniversity Hospitals Sussex NHS Foundation Trust, West Sussex, U.K.
Rob DanielsDepartment of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.
Kinan MokbelDepartment of Health and Care Professions, Faculty of Health and Life Sciences, University of Exeter, Exeter, U.K.; K.A.Mokbel@exeter.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimChronic kidney disease (CKD) contributes significantly to morbidity, mortality, and healthcare costs. CKD is not only an independent risk factor for cardiovascular disease (CVD) but also a severe complication for patients with CVD, impacting substantially their prognosis and quality of life. CASE REPORT: A 79-year-old male with a complex medical history, including asthma, hypertension, myocardial infarction, ischaemic heart disease, and recent atrial fibrillation, presented with new-onset exertional breathlessness and peripheral oedema following cardiac arrest and pacemaker insertion. Investigations, including medication reviews conducted shortly after in an outpatient setting, revealed severe renal impairment with creatinine levels at 250 μmol/l (reference range for adult males: 59-104), representing an initial acute kidney injury (AKI) that did not resolve and resulted in the diagnosis of stage 4 CKD (eGFR 25 ml/min/1.73 m

conclusionThis case highlights the importance of individualised treatment for patients with CKD alongside complex cardiovascular multi-morbidity. The administration of dapagliflozin and furosemide, together with careful adjustments to ramipril, were instrumental in stabilising the patient's renal function and alleviating symptoms. This case demonstrates how a multifaceted approach, continuous monitoring, and patient education are essential for achieving optimal outcomes in patients with CKD and cardiovascular comorbidities.

Indexed as

Cardiovascular DiseasesDyspneaEdemaHeart ArrestRenal Insufficiency, ChronicAgedHumansMaleMultimorbidityacute kidney injuryAKIcardiac arrestcardiovascular diseaseChronic kidney diseaseCKDCVDdifferential diagnosispacemakerperipheral oedemashortness of breath

Identifiers

PMID40010965
PMCPMC11884450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.