ArticleEuropean journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences2025
Prediction of surfactant-mediated dissolution of poorly soluble drugs from drug powder.
Article in European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Navigating Surfactant Selection in In Vitro Dissolution Testing: Mechanistic Insights and Practical Strategies.AAPS PharmSciTech · 2026Review
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3 authors.
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Abstract
Beyond rough "what if" estimation, in vitro dissolution is infrequently predicted. The objective was to assess the predictability of a powder dissolution model with a single diffusion layer thickness model, where dissolution of various drugs was facilitated by several surfactant micelles. Powder dissolution of three poorly water soluble drugs (i.e., posaconazole, ritonavir, and griseofulvin) was measured into buffer, as well as four surfactant solutions [i.e., sodium lauryl sulfate (SLS), polysorbate 80 (PS80), polyoxyethylene (10) lauryl ether (POE10), and cetyltrimethylammonium bromide (CTAB)]. Drug solubility, micelle sizing, and powder sizing were also performed. Prediction of drug dissolution employed the film dissolution model, applied to spherical drug particle fractions of the percent weight particle size distribution, and with a surfactant-mediated dissolution component. There were two competing models for diffusion layer thickness: fixed thickness (i.e., h
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