Evidence map›Paper›PMID 40009567›Full record

ArticleJournal of proteome research2025

Categorization and Characterization of Snake Venom Variability through Intact Toxin Analysis by Mass Spectrometry.

Luis L Alonso, Julien Slagboom, Nicholas R Casewell, Saer Samanipour, Jeroen Kool

Abstract read
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luis L AlonsoDivision of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081, HV, Amsterdam, The Netherlands.ORCID 0000-0003-3922-8099
Julien SlagboomDivision of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081, HV, Amsterdam, The Netherlands.
Nicholas R CasewellCentre for Snakebite Research and Interventions, Liverpool School of Tropical Medicine, L3 5QA, Pembroke Place, Liverpool, United Kingdom.
Saer SamanipourVan 't Hof Institute for Molecular Sciences, University of Amsterdam, Science Park 904, 1098 XH, Amsterdam, The Netherlands.ORCID 0000-0001-8270-6979
Jeroen KoolDivision of BioAnalytical Chemistry, Amsterdam Institute of Molecular and Life Sciences, Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081, HV, Amsterdam, The Netherlands.ORCID 0000-0002-0011-5612

Funding

Wellcome Trust
6 · The paper itself

Abstract

The variation in venom between and within snake species has significant implications for snakebite treatment. This highlights the critical importance of studying venom composition and its variations, not only for medical purposes but also from an evolutionary perspective. This study explores analytics for characterizing venom variability, focusing on venom toxin accurate masses, and emphasizes how the complexity of studying snake venom variability can be addressed by using liquid chromatography mass spectrometry (LC-MS) analysis with bioinformatics tools. This was demonstrated by investigating LC-MS data obtained from the venoms of 15 true cobras (

Indexed as

Mass SpectrometrySnake VenomsAnimalsBothropsChromatography, LiquidComputational BiologyElapid VenomsViper VenomsElapid VenomsSnake VenomsViper VenomsbioinformaticsLC-MSPCAsnake venom variationtoxin accurate mass

Identifiers

PMID40009567
PMCPMC11894662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.