Evidence map›Paper›PMID 40009551›Full record

Observational studyDiabetes care2025

Early Continuous Glucose Monitor Use in Children and Adolescents With Type 1 Diabetes: Rates of Initiation and Impact on Glycemic Outcomes.

Elizabeth A Mann, Saketh Rompicherla, Brian Miyazaki, Nicole Rioles, Holly Hardison, Lauren Golden, Jennifer Sarhis, Halis K Akturk, Joyce Lee, Daniel J DeSalvo and 3 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Diabetes care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Determinants, implementation strategies, and mechanisms of the 4T Program.Journal of clinical & translational endocrinology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Article
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  12. Revolutionizing Diabetes Care: From Tech to Therapeutics.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elizabeth A MannSchool of Medicine and Public Health, University of Wisconsin, Madison, WI.ORCID 0000-0001-6439-0747
Saketh RompicherlaT1D Exchange, Boston, MA.
Brian MiyazakiChildren's Hospital, Los Angeles, CA.
Nicole RiolesT1D Exchange, Boston, MA.
Holly HardisonT1D Exchange, Boston, MA.
Lauren GoldenNYU Langone Health, New York, NY.
Jennifer SarhisCohen Children's Medical Center, Queens, NY.
Halis K AkturkBarbara Davis Center, Aurora, CO.
Joyce LeeSusan B. Meister Child Health Evaluation and Research Center, C.S. Mott Children's Hospital, Ann Arbor, MI.
Daniel J DeSalvoTexas Children's Hospital, Baylor College of Medicine, Houston, TX.
Patricia GomezMiller School of Medicine, University of Miami, Miami, FL.
Osagie EbekozienT1D Exchange, Boston, MA.
Priya PrahaladStanford University, Stanford, CA.

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Childhood Diabetes Clinical & Molecular Research Training ProgramT32DK077586 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI Brigid Ellen Gregg, Scott B. Reeder · 2008 to 2026
$2.4M
Helmsley Charitable TrustNIDDK NIH HHS P30 DK020572NIDDK NIH HHS T32 DK077586T1D Exchange QI Collaborative
6 · The paper itself

Abstract

objectiveEarly initiation of continuous glucose monitor (CGM) after type 1 diabetes (T1D) diagnosis has been associated with lower hemoglobin A1C (HbA1c) in single-institution studies. This multicenter study evaluated the association between the timing of CGM initiation and HbA1c at 3 years postdiagnosis. RESEARCH DESIGN AND

methodsData were obtained from the T1D Exchange Quality Improvement Collaborative (T1DX-QI) electronic health record database from 25 pediatric centers and included children and adolescents ≤18 years old diagnosed with T1D in 2019 and 2020. CGM initiation and glycemic outcomes were followed for 3 years after diagnosis. Locally estimated scatterplot smoothing plots evaluated the relationship between timing of CGM initiation and HbA1c over time, and logistic regression models were used to adjust for potential confounders.

resultsThere were 4,164 people included in this analysis, mean age was 12.6 (SD 3.5) years, and 37% had public health insurance. Of the 93% (n = 3,877) who initiated CGM within 3 years of T1D diagnosis, 21% did so at 0-3 months, 14% at 3-6 months, 14% at 6-12 months, and 51% after 12 months. Median HbA1c at 3 years postdiagnosis was lower for the 0-3 and 3-6 months groups compared with the 6-12 months and non-CGM user groups (7.9%, 7.9%, 8.4%, and 9.5%, respectively). Adjusted odds of HbA1c >9% were lowest for the 0-3 months group followed by the 3-6 months group.

conclusionsIn summary, early initiation of CGM within the first 6 months of diagnosis is associated with improved HbA1c outcomes at 3 years postdiagnosis.

Indexed as

Blood GlucoseBlood Glucose Self-MonitoringDiabetes Mellitus, Type 1AdolescentChildChild, PreschoolFemaleGlycated HemoglobinGlycemic ControlHumansLongitudinal StudiesMaleBlood GlucoseGlycated Hemoglobin

Identifiers

PMID40009551
PMCPMC12034905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.