Evidence map›Paper›PMID 40009270›Full record

ArticleOdontology2025

Impact of demineralization, brushing, and remineralization sequences on dentin mineral retention and surface properties.

Soyeon Kim, Sri Larnani, Ji Eun Son, Napas Lappanakokiat, Van Mai Truong, Bo-Hyoung Jin, Young-Seok Park

Abstract read
In one paragraph

Article in Odontology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Soyeon KimDepartment of Oral Anatomy and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea, 03080.ORCID http://orcid.org/0000-0001-6377-9902
Sri LarnaniDepartment of Oral Anatomy and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea, 03080.ORCID http://orcid.org/0000-0003-1866-6006
Ji Eun SonDepartment of Integrated Dentistry, School of Dentistry, Seoul National University, Seoul, Republic of Korea, 03080.
Napas LappanakokiatDepartment of Oral Anatomy and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea, 03080.ORCID http://orcid.org/0000-0001-9346-3861
Van Mai TruongFaculty of Odonto-Stomatology, University of Health Sciences, Vietnam National University, Ho Chi Minh City, Vietnam, 700000.ORCID http://orcid.org/0000-0002-1473-9485
Bo-Hyoung JinDepartment of Preventative & Public Health Dentistry and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea, 03080.
Young-Seok ParkDepartment of Oral Anatomy and Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Republic of Korea, 03080. ayoayo7@snu.ac.kr.ORCID http://orcid.org/0000-0002-0148-7848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the effects of different treatment sequences involving demineralization, brushing, and remineralization on the calcium and phosphorus (Ca/P) content, surface roughness, and microhardness of dentin specimens. Bovine dentin samples were subjected to the following five treatment conditions: control, demineralization, demineralization followed by remineralization, demineralization followed by brushing then remineralization, and demineralization followed by remineralization then brushing. X-ray fluorescence spectroscopy was then utilized to assess the elementary composition changes, while scanning electron microscopy provided microstructural analyses. Surface roughness and microhardness were also quantified to assess the physical changes in dentin. The control group retained significantly higher Ca/P content compared with all treated groups, indicating that demineralization, regardless of subsequent treatment, leads to a substantial loss of hydroxyapatite. Among the treated groups, those that underwent remineralization immediately after demineralization manifested higher Ca/P retention compared with those that included brushing before remineralization. Additionally, microhardness measurements indicated that post-demineralization brushing negatively affected dentin's microhardness. The sequence of demineralization, brushing, and remineralization treatments significantly affects Ca/P retention in dentin, along with its surface roughness and microhardness. Pre-remineralization brushing diminished mineral recovery, whereas exposure to mineral-rich beverage immediately after demineralization resulted in greater mineral deposition.

Indexed as

DentinToothbrushingTooth DemineralizationTooth RemineralizationAnimalsCalciumCattleHardnessIn Vitro TechniquesMicroscopy, Electron, ScanningPhosphorusSpectrometry, X-Ray EmissionSurface PropertiesCalciumPhosphorusDemineralizationDentinRemineralizationX-ray fluorescence spectroscopy

Identifiers

PMID40009270
PMCPMC12450817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.