Evidence map›Paper›PMID 40009198›Full record

ArticleCurrent microbiology2025

Deciphering Probiotic Effects of Sulfitobacter pontiacus Strain BL28 on the Host Sea Cucumber Apostichopus japonicus.

Tomoo Sawabe, Rika Kudo, Juanwen Yu, Thach Nguyen, Andrea Rossi, Yuichi Sakai, Sayaka Mino

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In one paragraph

Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tomoo SawabeLaboratory of Microbiology, Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Japan. sawabe@fish.hokudai.ac.jp.
Rika KudoLaboratory of Microbiology, Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Japan.
Juanwen YuLaboratory of Microbiology, Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Japan.
Thach NguyenIUF-Leibniz Research Institute for Environmental Medicine, Dusseldorf, Germany.
Andrea RossiIUF-Leibniz Research Institute for Environmental Medicine, Dusseldorf, Germany.
Yuichi SakaiHakodate Fisheries Research, Hokkaido Research Organization, Local Independent Administrative Agency, Hakodate, Japan.
Sayaka MinoLaboratory of Microbiology, Faculty of Fisheries Sciences, Hokkaido University, Hakodate, Japan. sayaka.mino@fish.hokudai.ac.jp.

Funding

MEXT Kaken JP19K22262
6 · The paper itself

Abstract

Recently, sea cucumber has been an increasingly important marine invertebrate in the fields of EcoDevo and fisheries studies. After the discovery of Sulfitobacter pontiacus strain BL28, which is a growth-promoting probiotic bacteria isolated from blastula of Apostichopus japonicus, host-microbes interaction has become a major new focus of study to be unveiled. Previous genome assessments of the strain BL28 hypothesized involvements of cobalamin/B12 biosynthesis, type IV secretion system, polyhydroxybutyrate production, and sulfate metabolism for host growth promotions. Here, we performed A. japonicus host transcriptome after five weeks of supplementation with S. pontiacus BL28. Unexpectedly, the host transcriptome revealed significant gene regulations of the BL28 supplementation on the host lipid and chondroitin metabolisms and transcriptionally "rest" status of heat shock protein genes un-expressed. Physiological and environmental crossover by the S. pontiacus BL28 supplementation may trigger stress-free growth promotion in the host sea cucumber. These symbiotics-type probiotics could help herald the future eco-friendly aquaculture of sea cucumber.

Indexed as

ProbioticsRhodobacteraceaeStichopusAnimalsHost Microbial InteractionsSymbiosisTranscriptome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.