Evidence map›Paper›PMID 40009143›Full record

ArticlePediatric surgery international2025

The predictive value of the aspartate aminotransferase to platelet ratio index combined with liver biochemical indexes for 2 years native liver survival in patients with biliary atresia.

Bingliang Li, Yingyu Jia, Hongwei Xi, Hongxia Ren

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Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Bingliang LiDepartment of Neonatal Surgery, Shanxi Provincial Children's Hospital, Taiyuan, China.
Yingyu JiaDepartment of Neonatal Surgery, Shanxi Provincial Children's Hospital, Taiyuan, China.
Hongwei XiDepartment of General Surgery, Shanxi Provincial Children's Hospital, Taiyuan, China.
Hongxia RenDepartment of Neonatal Surgery, Shanxi Provincial Children's Hospital, Taiyuan, China. renhongxia100@sina.com.

Funding

Funding support for national key clinical specialty construction units GZ202401Shanxi Provincial Children's Hospital Institutional Project 2023002Shanxi Provincial Health Commission Project 2022074
6 · The paper itself

Abstract

objectiveTo investigate the predictive value of the aspartate aminotransferase-to-platelet ratio index (APRI) in combination with liver biochemical indices on the time to native liver survival (NLS) in patients with biliary atresia (BA) two years after Kasai portoenterostomy (KPE).

methodsThe clinical data from 2013 to 2022 at Shanxi Children's Hospital were analyzed. Patients were divided into two groups based on whether they survived with their native liver 2 years after KPE. General information and laboratory findings were reviewed before and then monthly after KPE until 3 months postoperatively. APRI was calculated.

resultsA total of 125 children with type III BA were included. There were statistically significant differences in the preoperative AST, GGT, APRI, liver fibrosis stage and jaundice clearance rate between two groups. The AUC of APRI at 3 months for predicting NLS was 0.732. The AUC of APRI at 3 months in predicting the 2-year NLS time in children with BA was higher than the single index.

conclusionThe prediction value of APRI for 2-year NLS time increases when combined with other indicators, and is better than single indicator, the prediction value is strongest when APRI is combined with all indicators.

Indexed as

Aspartate AminotransferasesBiliary AtresiaLiverPortoenterostomy, HepaticBiomarkersChild, PreschoolFemaleHumansInfantMalePlatelet CountPredictive Value of TestsRetrospective StudiesAspartate AminotransferasesBiomarkersAPRIBiliary atresiaLiver biochemical indexesNative liver survivalPredictive value

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.