Evidence map›Paper›PMID 40008888›Full record

ArticleInfection and immunity2025

Identification of glyoxalase A in group B

Madeline S Akbari, Luke R Joyce, Brady L Spencer, Amanda Brady, Kevin S McIver, Kelly S Doran

Abstract read
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Host methylglyoxal activates theProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. A putativeFrontiers in immunology · 2026
    Article
  6. Cell envelope maintenance by PhoP is essential forProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Review
  8. Article
  9. A murine model of adult gastrointestinal colonization by Group BbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Madeline S AkbariDepartment of Immunology and Microbiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0001-6706-5704
Luke R JoyceDepartment of Immunology and Microbiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-9346-671X
Brady L SpencerDepartment of Immunology and Microbiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0003-4374-6403
Amanda BradyDepartment of Immunology and Microbiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kevin S McIverCell Biology and Molecular Genetics, Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA.ORCID 0000-0002-4769-4463
Kelly S DoranDepartment of Immunology and Microbiology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0003-4232-6837

Funding

Training Program in Perinatal Biology and MedicineT32HD007186 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Paul Joseph Rozance · 1985 to 2026
$6.5M
PRD-Containing Virulence Regulators of Pathogenic StreptococciR01AI047928 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MCIVER, KEVIN S. · 2001 to 2023
$6.5M
Host and bacterial mechanisms governing Group B streptococcal persistence in the female genital tractR01AI153332 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2021 to 2025
$2.9M
Modulation of Blood-Brain Barrier Defense and Dysfunction during Bacterial MeningitisR01NS116716 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DORAN, KELLY S · 2020 to 2024
$1.9M
Host-pathogen interactions during GBS diabetic wound infectionsF31AI178881 · NIAID · UNIVERSITY OF COLORADO DENVER · PI AKBARI, MADELINE SOHAYLA · 2024 to 2025
$51k
American Heart Association (AHA) 23POST1013835HHS | NIH | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) T32HD007186HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) F31AI178881HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI153332HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01NS116716NIAID NIH HHS F31 AI178881NIAID NIH HHS R01 AI047928NIAID NIH HHS R01 AI153332NINDS NIH HHS R01 NS116716
6 · The paper itself

Abstract

Group B

Indexed as

Bacterial ProteinsLactoylglutathione LyasePyruvaldehydeStreptococcal InfectionsStreptococcus agalactiaeAnimalsBacteremiaDisease Models, AnimalDNA Transposable ElementsFemaleHumansMiceMutationVirulenceVirulence FactorsBacterial ProteinsDNA Transposable ElementsLactoylglutathione LyasePyruvaldehydeVirulence Factorsbacteremiaglycolysisglyoxalasegroup B Streptococcushost-pathogen interactionsmethylglyoxalneutrophilsStreptococcus agalactiae

Identifiers

PMID40008888
PMCPMC11977320

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.