Evidence map›Paper›PMID 40008876›Full record

ArticleApplied and environmental microbiology2025

Inhibition of pneumococcal growth and biofilm formation by human isolates of

João Borralho, Sara Handem, João Lança, Bárbara Ferreira, Catarina Candeias, Adriano O Henriques, N Luisa Hiller, Carina Valente, Raquel Sá-Leão

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. RggmBio · 2026
    Article
  3. mBio · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

João Borralho *Laboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Sara Handem *Laboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
João Lança *Laboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.ORCID 0009-0009-7706-7792
Bárbara FerreiraLaboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Catarina CandeiasLaboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.
Adriano O HenriquesLaboratory of Microbial Development, Instituto de Tecnologia Química e Biológica António Xavier, Oeiras, Portugal.
N Luisa HillerDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.ORCID 0000-0001-6572-1368
Carina ValenteLaboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.ORCID 0000-0003-1864-6080
Raquel Sá-LeãoLaboratory of Molecular Microbiology of Human Pathogens, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Oeiras, Portugal.ORCID 0000-0001-9804-827X

Funding

Fundacao para a Ciencia e a Tecnologia 2021.07866.BD PD/BD/128365/2017 UI/BD/153385/20222 2020.05293.BD PD/BD/148434/2019 SFRH/BPD/115280/2Fundacao para a Ciencia e a Tecnologia LA/P/0097/2020Fundacao para a Ciencia e a Tecnologia PTDC/BIA-MIC/30703/2017Fundacao para a Ciencia e a Tecnologia UIDB/04612/2020
6 · The paper itself

Abstract

In a world facing the unprecedented threat of antibiotic-resistant bacteria, targeted approaches to control colonization and prevent disease caused by common pathobionts offer a promising solution. IMPORTANCE:

Indexed as

AntibiosisBiofilmsStreptococcus mitisStreptococcus oralisStreptococcus pneumoniaeBacteriocinsHumansPneumococcal InfectionsBacteriocinsbacteriocinbiofilmbiotherapeuticcolonizationStreptococcus mitisStreptococcus oralisStreptococcus pneumoniae

Identifiers

PMID40008876
PMCPMC11921387

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.