Evidence map›Paper›PMID 40008701›Full record

ReviewMemorias do Instituto Oswaldo Cruz2025

Free-living amoebae: a journey into historical aspects and to current discoveries.

Helena Lúcia Carneiro Santos

Abstract readReview
In one paragraph

Review in Memorias do Instituto Oswaldo Cruz, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Helena Lúcia Carneiro SantosFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Doenças Parasitárias, Rio de Janeiro, RJ, Brasil.ORCID http://orcid.org/0000-0002-5240-5662

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Free-living amoebas (FLA) are ubiquitous protists found in the environment. They have shown exceptional resistance to environmental challenges and play significant roles in controlling microbial populations through their predatory behaviour and microbicidal activity in both soil and aquatic ecosystems environments. However, although rare, a limited group of FLA can cause serious infections in the central nervous system and other diseases, particularly in immunocompromised individuals with high mortality rates. They can also cause keratitis in otherwise healthy individuals. This review offers a comprehensive overview of freshwater naked amoebae but does not cover all aspects in detail. Its goal is to provide a historical context for our current understanding while addressing the most critical elements of FLA biology, their pathogenic potential, and their interactions with important human pathogens.

Indexed as

AmoebaAnimalsFresh WaterHumans

Identifiers

PMID40008701
PMCPMC11852317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.