Evidence map›Paper›PMID 40008524›Full record

ArticleJournal of the American Heart Association2025

Incidence But Not Severity of Intracerebral Hemorrhage Shows a Strong Pattern of Seasonal Variation.

Ariane Martinez Oeckel, Bjoern Misselwitz, Christian Foerch

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ariane Martinez OeckelDepartment of Neurology Goethe University Frankfurt am Main Germany.ORCID 0000-0003-3554-1432
Bjoern MisselwitzFederal State Consortium of Quality Assurance Hesse Eschborn Germany.
Christian FoerchDepartment of Neurology Goethe University Frankfurt am Main Germany.ORCID 0000-0002-3770-7857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA strong risk factor for intracerebral hemorrhage (ICH) is elevated arterial blood pressure, which is known to vary by season, with highest values in winter months. The objective was to assess seasonal trends of ICH incidence, clinical severity, and case fatality according to demographic and clinical characteristics.

methodsThis study was conducted on adult patients hospitalized for ICH between 2003 and 2022. Cases were identified from a stroke inpatient quality assurance registry covering the entire Federal State of Hesse, Germany. Population data were derived from the Hessian Bureau of Statistics. Incidence rates (IRs) per 100 000 person-years of ICH, recorded with 4-digit

resultsA total of 33 444 patients were included (mean age, 72.4±13.6 years, 52% men). ICH IR correlated with the season of occurrence, demonstrating a peak in winter (IR winter, 34.6 [95% CI, 33.9-35.4], IR summer, 29.4 [95% CI, 28.7-30.1];

conclusionsThis large cohort study demonstrates a seasonal incidence peak of ICH in winter. Whether ICH can be prevented by better control of arterial blood pressure in seasons with expected incidence peaks will require further studies.

Indexed as

Cerebral HemorrhageSeasonsAgedAged, 80 and overFemaleGermanyHumansIncidenceMaleMiddle AgedRegistriesRetrospective StudiesRisk FactorsSeverity of Illness Indexcase fatalityhypertensionincidenceintracerebral hemorrhageseasonal variationstroke

Identifiers

PMID40008524
PMCPMC12132777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.