Observational studyJournal of the American Heart Association2025
OPTILOW: A Low-Profile Approach for Implanting Optimus-L Stents in Infants and Children.
Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Left ventricular outflow tract stenting in late presenting transposition physiology with ventricular shunt and pulmonary stenosis: a case series.Frontiers in cardiovascular medicine · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStent implantation poses challenges in small children due to their limited vessel size and rapid growth. This multicenter study evaluates in vivo efficacy of implanting Optimus-L stents in small patients using a low-profile approach.
methodsWe retrospectively reviewed data from children weighing ≤20 kg with congenital heart stenotic lesions who received Optimus-L stents manually mounted on small-sized balloon catheters (diameter ≤12 mm) using a hand-actuated compression tool and implanted through small-sized sheaths (≤8 Fr) at our institutions between May 2022 and January 2024. Stent performance was assessed.
resultsWe identified 28 patients (67.8% male) with median age and weight of 3.4 years (interquartile range [IQR], 1.5-5.5) and 12.9 kg (IQR, 9.1-16.4). Six (21.4%) were infants, 11 (39.3%) ≤10 kg. Stenotic lesions included 16 branch pulmonary arteries, 9 aortic isthmus, 2 right ventricular outflow tracts, and 1 Glenn anastomosis. Percentage of stenosis was 50% (IQR, 36%-58%). All implantations were successful without complications. The procedures mostly used 7 Fr sheaths for stents on 6, 7, and 8 mm balloons and 8 Fr sheaths for 9, 10, 12 mm balloons. Median stent expansion percentage was 95% (IQR, 90%-96%). Median vessel diameters increased from 4.6 mm (IQR, 3.8-5.1) to 8.8 mm (IQR, 7.5-9.5) (
conclusionsOptimus-L stents can safely treat arterial and venous stenosis in infants and small children via a low-profile approach with good outcomes.
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