ArticleHypertension (Dallas, Tex. : 1979)2025
Hypertension Prevention and Healthy Life Expectancy in Black Adults: The Jackson Heart Study.
Kathryn Foti, Yiyi Zhang, Susan E Hennessy, Lisandro D Colantonio, Lama Ghazi, Shakia T Hardy, Milla E Arabadjian, Rushelle L Byfield, Valy Fontil, Cora E Lewis and 3 more
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In one paragraphArticle in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
13 authors.
Kathryn FotiDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-6380-2735 Yiyi ZhangDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-8663-5001 Susan E HennessyDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-6342-7138 Lisandro D ColantonioDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0001-8742-1788 Lama GhaziDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-9930-3575 Shakia T HardyDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0001-9211-0474 Milla E ArabadjianDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0003-3307-1406 Rushelle L ByfieldDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-4673-7118 Valy FontilDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0003-0795-3237 Cora E LewisDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-2301-5796 Daichi ShimboDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0001-6302-8834 Paul MuntnerDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0002-4711-5492 Brandon K BellowsDepartment of Epidemiology, University of Alabama at Birmingham School of Public Health, AL (K.F., L.D.C., L.G., C.E.L., P.M.).ORCID 0000-0003-1395-6047 Funding
Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6MIncorporation of a Hypertension Working Group into the Jackson Heart StudyR01HL117323 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LEWIS, CORA E, OGEDEGBE, OLUGBENGA G. · 2013 to 2024
$7.2MImproving Blood Pressure Screening and Treatment Strategies in Young AdultsR01HL158790 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI AN, JAEJIN, ZHANG, YIYI · 2021 to 2025
$3.5MInforming optimal first-line antihypertensive therapy: A rigorous comparative effectiveness analysis of ARBs vs. ACEIs on long-term risk of dementia, cancer, heart disease, and quality of lifeR01AG074989 · NIA · UNIVERSITY OF PENNSYLVANIA · PI BRESS, ADAM P, COHEN, JORDANA B. · 2022 to 2025
$3.3MComparing the value of intensive systolic blood pressure treatment implementation strategiesK01HL140170 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BELLOWS, BRANDON K · 2018 to 2022
$709kAmerican Heart Association-American Stroke Association 878088NCATS NIH HHS KL2 TR001874NHLBI NIH HHS HHSN268201800010INHLBI NIH HHS HHSN268201800011CNHLBI NIH HHS HHSN268201800011INHLBI NIH HHS HHSN268201800012CNHLBI NIH HHS HHSN268201800012INHLBI NIH HHS HHSN268201800014CNHLBI NIH HHS HHSN268201800014INHLBI NIH HHS HHSN268201800015INHLBI NIH HHS K01 HL140170NHLBI NIH HHS R01 HL117323NHLBI NIH HHS R01 HL158790NIA NIH HHS R01 AG074989NIMHD NIH HHS HHSN268201800013I
6 · The paper itselfAbstract
backgroundThe impact of preventing hypertension and maintaining normal blood pressure (BP) on life expectancy and healthy life expectancy (HLE) among Black adults, who are disproportionately affected by hypertension, has not been quantified.
methodsWe used a discrete event simulation to estimate life expectancy and HLE among a cohort of Black adults from the Jackson Heart Study (n=4933) from age 20 to 100 years or until death. We modeled preventing hypertension as having BP <130/80 mm Hg and maintaining normal BP as having BP <120/80 mm Hg across the lifespan. In the primary analysis, we assumed that lowering BP decreased the risk of cardiovascular disease events, resulting in life expectancy and HLE gains. In a secondary analysis, we assumed that preventing hypertension and maintaining normal BP directly reduced both cardiovascular disease and mortality risk.
resultsAt age 20 years, the projected average life expectancy was age 80.8 (95% uncertainty interval [UI], 80.6-81.1) years, and HLE was 70.5 (95% UI, 70.3-70.7) healthy life years. In the primary analysis, preventing hypertension and maintaining normal BP added 0.9 (95% UI, 0.8-1.1) and 1.1 (95% UI, 0.9-1.3) years to life expectancy, respectively, and 2.7 (95% UI, 2.6-2.9) and 2.9 (95% UI, 2.7-3.1) healthy life years to HLE, respectively. In the secondary analysis, preventing hypertension and maintaining normal BP added 4.5 (95% UI, 4.3-4.6) and 4.6 (95% UI, 4.4-4.8) years to life expectancy, respectively, and 5.7 (95% UI, 5.6-5.8) and 5.9 (95% UI, 5.7-6.0) healthy life years to HLE, respectively.
conclusionsPreventing hypertension and maintaining normal BP were projected to increase life expectancy and HLE among Black adults.
Indexed as
Black or African AmericanHypertensionLife ExpectancyAdultAgedAged, 80 and overBlood PressureCardiovascular DiseasesCohort StudiesFemaleHumansMaleMiddle AgedMississippiYoung Adultblood pressurehealthy life expectancyhypertensionlife expectancy
Identifiers
PMID40008433
PMCPMC12078003
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