ArticleClinical kidney journal2025
Nutritional outcomes between different techniques of intradialytic amino acid replacement: a randomized controlled trial.
Article in Clinical kidney journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- An International Expert Consensus Statement and Guidance Document on Implementation of Nutritional Supplementation in Patients on Dialysis.Kidney international reports · 2026Article
- Food Frequency Questionnaire to Estimate Dietary Adherence in Hemodialysis Patients: A Pilot Study.Nutrients · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Amino acid (AA) depletion during dialysis deteriorates the protein-energy status of haemodialysis (HD) patients. This study aimed to determine whether intradialytic amino acid (IDAA) replacement by continuous infusion versus acute load could provide better nutritional outcomes. Methods: HD patients with mild protein-energy wasting, defined as a serum albumin level of 3.5-3.9 mg/dl despite 7-point subjective global assessment in category A or a malnutrition inflammation score ≤5, were randomly assigned to receive IDAA by continuous infusion or acute load for 3 months. In continuous infusion ( Results: The mean age of patients was 68.9 ± 12.7 years and the average body mass index was 22.8 ± 4.4 kg/m Conclusions: IDAA using continuous infusion appears to be superior to acute load in terms of serum albumin and muscle mass improvement. The impact of IDAA on hard clinical outcomes may require larger scale with a longer period of study (TCTR20230401003).
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