An unusual mediastinal giant parathyroid adenoma: A rare case report.

Ahmad Huneity, Yaman M Alahmad, Issam Al Bozom, Abdelkareem Alhyari, Ayoub Alaoud, Rajendra Kumar

Abstract readCase Reports

In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Ahmad HuneityRadiology Department, Hamad Medical Corporation, Doha, Qatar.

Yaman M AlahmadRadiology Department, Hamad Medical Corporation, Doha, Qatar.

Issam Al BozomPathology Department, Hamad Medical Corporation, Doha, Qatar.

Abdelkareem AlhyariPathology Department, Hamad Medical Corporation, Doha, Qatar.

Ayoub AlaoudPathology Department, Hamad Medical Corporation, Doha, Qatar.

Rajendra KumarRadiology Department, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroid adenoma is the most common cause of primary hyperparathyroidism. Giant parathyroid adenoma is considered a rare subtype of parathyroid adenomas that weigh more than 3.5 grams and cause a small number of adenoma related hyperparathyroidism. We present a case of 68-year-old asymptomatic male patient who had hypercalcemia and markedly high parathyroid hormone level on routine blood testing. Radiological investigations demonstrated a large mediastinal mass that showed peripheral high uptake on sestamibi scan. Histopathology confirmed the diagnosis of giant parathyroid adenoma. Giant parathyroid adenomas can have an atypical radiological appearance and present as a mediastinal mass that resembles other mediastinal masses, making it important to include in the list of possible diagnoses.

Indexed as

Ectopic parathyroid adenomaEctopic parathyroid glandGiant parathyroid adenomaHyperparathyroidismParathyroid gland

Identifiers

PMID40008333

DOI10.1016/j.radcr.2025.01.068

PMCPMC11851221

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