Evidence map›Paper›PMID 40008330›Full record

ArticleBrain communications2025

Neurovascular phase coherence is altered in Alzheimer's disease.

Juliane Bjerkan, Bernard Meglič, Gemma Lancaster, Jan Kobal, Peter V E McClintock, Trevor J Crawford, Aneta Stefanovska

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. An order parameter for synchronisation of angular velocities.The European physical journal. Special topics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juliane BjerkanDepartment of Physics, Lancaster University, LA1 4YB Lancaster, UK.
Bernard MegličDepartment of Neurology, University Medical Centre, 1525 Ljubljana, Slovenia.
Gemma LancasterDepartment of Physics, Lancaster University, LA1 4YB Lancaster, UK.
Jan KobalDepartment of Neurology, University Medical Centre, 1525 Ljubljana, Slovenia.
Peter V E McClintockDepartment of Physics, Lancaster University, LA1 4YB Lancaster, UK.
Trevor J CrawfordDepartment of Psychology, Lancaster University, LA1 4YF Lancaster, UK.
Aneta StefanovskaDepartment of Physics, Lancaster University, LA1 4YB Lancaster, UK.ORCID https://orcid.org/0000-0001-6952-8370

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease is the commonest form of dementia, but its cause still remains elusive. It is characterized by neurodegeneration, with amyloid-beta and tau aggregation. Recently, however, the roles of the vasculature and the neurovascular unit are being highlighted as important for disease progression. In particular, there is reduced microvascular density, and altered gene expression in vascular and glial cells. Structural changes naturally impact the functioning of the neurovascular unit, and the goal of the study was to quantify the corresponding changes

Indexed as

brain oxygenationmulti-scale oscillatory analysisneurovascular unitphase coherencetime-frequency analysis

Identifiers

PMID40008330
PMCPMC11852277

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.