ArticleBrain communications2025
Anti-seizure medication tapering correlates with daytime delta band power reduction in the cortex.
Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Abnormal local markers of sleep homeostasis in patients with focal epilepsy.Brain communications · 2026Article
- Dual mechanism of anti-seizure medications in controlling seizure activity.Brain communications · 2026Article
- Multi-centre normative brain mapping of intracranial EEG lifespan patterns in the human brain.Brain structure & function · 2025Article
- Electroencephalographic Biomarkers for Neuropsychiatric Diseases: The State of the Art.Bioengineering (Basel, Switzerland) · 2025Review
- Optimising anti-seizure medication timing using a dynamic network model of seizure rhythms.Frontiers in network physiology · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anti-seizure medications are the primary treatment for epilepsy; yet medication tapering effects have not been investigated in a dose, region and time-dependent manner, despite their potential impact on research and clinical practice. We examined over 3000 h of intracranial EEG recordings in 32 subjects during long-term monitoring, of which 22 underwent concurrent anti-seizure medication tapering. We estimated anti-seizure medication plasma levels based on known pharmaco-kinetics of all the major anti-seizure medication types. We found an overall decrease in the power of delta band (
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