Evidence map›Paper›PMID 40008318›Full record

ArticleResuscitation plus2025

Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest.

Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Resuscitation plus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hao-Wei LeeDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Ming-Jen KuoDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Pai-Feng HsuDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
I-Hsin LeeDepartment of Emergency, Taipei Veterans General Hospital, Taipei, Taiwan.
Chih-Yu YangSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Teh-Fu HsuSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chorng-Kuang HowSchool of Medicine, College of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yenn-Jiang LinDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chin-Chou HuangDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Comprehensive studies about renal-function changes in the context of out-of-hospital cardiac arrest (OHCA) have been lacking. Therefore, we investigated the impact of renal function on clinical outcomes among patients with OHCA. Method: This retrospective cohort study enrolled consecutive patients with OHCA between June 2017 and December 2021. Acute kidney injury (AKI) was defined based on the "Kidney Disease: Improving Global Outcomes (KDIGO)" guidelines. AKI recovery was defined as a decrease in serum creatinine below the level determined in the definition of AKI. Clinical outcomes included neurological outcomes and all-cause mortality. Result: A total of 258 patients were enrolled, including 35 patients with underlying end-stage renal disease (ESRD). Among patients without ESRD, 82.5% developed AKI, of which 31.0% achieved AKI recovery, while 61.0% were discharged with impaired renal function. Multivariable analysis using regression models revealed that unfavorable neurological outcomes at discharge and higher mortality at 2 years were associated with AKI (odds ratio [OR] 7.684, 95% confidence interval (CI) 2.683-22.010, Conclusion: AKI, AKI without recovery, and impaired pre-discharge renal function were significantly correlated with worse clinical outcomes in OHCA among patients without ESRD, while underlying ESRD did not lead to worse clinical outcomes.

Indexed as

Acute kidney injuryEnd-stage renal diseaseOut-of-hospital cardiac arrestRenal function

Identifiers

PMID40008318
PMCPMC11850737

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.