Evidence map›Paper›PMID 40008293›Full record

ArticleJournal of biomedical optics2025

Er:YAG laser biofilm removal from zero-gap periodontal/peri-implant model system mimicking clinical attachment loss.

Marko Volk, Dominik Šavli, Katja Molan, Saša Terlep, Špela Levičnik-Höfferle, Mojca Trost, Boris Gašpirc, Matjaž Lukač, Matija Jezeršek, David Stopar

Abstract read
In one paragraph

Article in Journal of biomedical optics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marko VolkUniversity of Ljubljana, Department of Microbiology, Biotechnical Faculty, Ljubljana, Slovenia.
Dominik ŠavliUniversity of Ljubljana, Faculty of Mechanical Engineering, Ljubljana, Slovenia.ORCID 0009-0004-1724-8667
Katja MolanUniversity of Novo Mesto, Faculty of Health Sciences, Novo Mesto, Slovenia.ORCID 0000-0001-7883-9410
Saša TerlepFotona d.o.o., Ljubljana, Slovenia.
Špela Levičnik-HöfferleFotona d.o.o., Ljubljana, Slovenia.
Mojca TrostUniversity of Ljubljana, Department of Oral Medicine and Periodontology, Medical Faculty, Ljubljana, Slovenia.
Boris GašpircUniversity of Ljubljana, Department of Oral Medicine and Periodontology, Medical Faculty, Ljubljana, Slovenia.ORCID 0000-0001-8843-8258
Matjaž LukačFotona d.o.o., Ljubljana, Slovenia.
Matija JezeršekUniversity of Ljubljana, Faculty of Mechanical Engineering, Ljubljana, Slovenia.
David StoparUniversity of Ljubljana, Department of Microbiology, Biotechnical Faculty, Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance: Here, we present a photoacoustic method to remove biofilms from periodontal and peri-implant-constrained geometries. Aim: We aim to remove biofilms from narrow periodontal and peri-implant model systems with the application of Er:YAG ultrashort laser pulses. Approach: Construction of zero-gap model system from PDMS and titanium, growth of biofilms on titanium surfaces, and removal of biofilms with Er:YAG USP, 20 mJ, 15 Hz, and 10 s were performed. Results: The results suggest that geometry, the vertical position of the laser fiber tip, and the evolution of the primary cavitation bubble significantly affect cleaning effectiveness. Cleaning was higher in the wedge part of the model system. In the zero-gap part of the model system, biofilm cleaning effectiveness was highest at the position of the laser fiber tip and decreased above and below the fiber tip. The dimension of the space in which the cavitation bubble develops determines the size and dynamics of the expanded cavitation bubble and consequently the biofilm cleaning effectiveness. Conclusions: The obtained results suggest a very good biofilm removal effectiveness in difficult-to-reach narrow geometries mimicking clinical attachment loss in the periodontal/peri-implant pocket.

Indexed as

BiofilmsDental ImplantsLasers, Solid-StateHumansModels, BiologicalTitaniumDental ImplantsTitaniumattachment lossbiofilmEr:YAG laserin vitro modelphotoacoustic removal

Identifiers

PMID40008293
PMCPMC11853840

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.