Evidence map›Paper›PMID 40008157›Full record

Trial reportTopics in spinal cord injury rehabilitation2025

The Effect of a Low-Glycemic Index Diet on Postprandial Hypotension in Individuals With Chronic Spinal Cord Injury: Results From a Pilot Study.

Matthew Farrow, Jia Li, Sana Chahande, Raquel Minarsch, Tonya Orchard, Jan Schwab, Ceren Yarar-Fisher

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Topics in spinal cord injury rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. How to treat cardiovascular autonomic failure in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matthew FarrowDepartment of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio.
Jia LiDepartment of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio.
Sana ChahandeDepartment of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio.
Raquel MinarschDepartment of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio.
Tonya OrchardDepartment of Human Sciences, College of Education and Human Ecology, The Ohio State University, Columbus, Ohio.
Jan SchwabDepartment of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio.
Ceren Yarar-FisherDepartment of Physical Medicine and Rehabilitation, College of Medicine, The Ohio State University, Columbus, Ohio.

Funding

Reducing Infection Susceptibility by Immune Function Restoration in Spinal Cord InjuryR01NS118200 · NINDS · OHIO STATE UNIVERSITY · PI SCHWAB, JAN · 2020 to 2024
$1.9M
NINDS NIH HHS R01 NS118200
6 · The paper itself

Abstract

Background: One in two individuals with spinal cord injury (SCI) experiences postprandial hypotension (PPH), a decline (>20 mm Hg) in systolic blood pressure (SBP) within 2 hours after eating. Consuming meals with a low glycemic index (GI) could prevent or lessen PPH. Objectives: To determine the effect of a low-GI diet on PPH and postprandial glucose and insulin in individuals with chronic SCI (>1 year postinjury). Methods: Eleven participants (6 males, 5 females; age 43 ± 11 years) with chronic SCI (C4-C7, 7; T4-T12, 4) took part in a randomized crossover study (low GI vs. high GI). On each occasion, BP, glucose, and insulin were measured in the fasted state and for 2 hours after consuming a breakfast meal (60% carbohydrate, 28% fat, 12% protein) in laboratory-controlled conditions. Participants wore an ambulatory BP monitor and continuous glucose monitor for 3 days at home, and consumed study meals that were macronutrient-matched across conditions. Results: The maximum decrease in systolic blood pressure (SBP) following the laboratory-controlled breakfast meals tended to be lower in the low-GI (14 ± 12 mm Hg) compared to the high-GI (24 ± 25 mm Hg) diet ( Conclusion: A low-GI meal may be an effective solution to reduce the magnitude of PPH and peak glucose concentrations in individuals with chronic SCI.

Indexed as

Glycemic IndexHypotensionPostprandial PeriodSpinal Cord InjuriesAdultBlood GlucoseBlood PressureChronic DiseaseCross-Over StudiesFemaleHumansInsulinMaleMiddle AgedPilot ProjectsBlood GlucoseInsulinblood pressure regulationcardiovascular diseasemetabolic health

Identifiers

PMID40008157
PMCPMC11848139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.