Evidence map›Paper›PMID 40007976›Full record

ReviewJournal of neuroendovascular therapy2025

N-butyl Cyanoacrylate Use in Various Neuroendovascular Diseases.

Satoshi Koizumi, Motoyuki Umekawa, Shigeta Fujitani, Hideaki Ono, Satoru Miyawaki, Nobuhito Saito

Abstract readReview
In one paragraph

Review in Journal of neuroendovascular therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Preoperative Embolization for Tentorial and Subtentorial Tumors.Journal of neuroendovascular therapy · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Satoshi KoizumiDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Motoyuki UmekawaDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Shigeta FujitaniDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Hideaki OnoDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Satoru MiyawakiDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.
Nobuhito SaitoDepartment of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review discusses the use of N-butyl cyanoacrylate (NBCA) in various neuroendovascular treatments. Despite the increase in the ONYX, NBCA continues to have significant usage. It is particularly useful for the treatment of arteriovenous malformations (AVM) and dural arteriovenous fistulas (dAVFs). Comparative studies have suggested that ONYX and NBCA are equally effective and safe for the treatment of AVM. However, the choice between the two depends on specific situations, such as the characteristics of the feeding arteries. NBCA is recommended for tortuous feeders, high-flow fistulous feeders, and feeders with a short margin of reflux, owing to the procedural risks posed by ONYX. The use of NBCA is also prominent in dAVF embolization. While achieving total occlusion solely with NBCA can be challenging, NBCA adheres to the vessel wall and encourages thrombus formation, aiding in fistula obliteration. In addition to AVM and dAVF, NBCA is used to treat chronic subdural hematoma and craniofacial vascular injuries. Embolization using NBCA is beneficial because of its deep penetration into the target tissue. For craniofacial injuries, NBCA embolization provides secure hemostasis within a short time. Neuroendovascular physicians should understand the characteristics of NBCA as a liquid embolic material and have expertise in the technical aspects of NBCA embolization, even in the ONYX era.

Indexed as

arteriovenous malformationchronic subdural hematomadural arteriovenous fistulaN-butyl cyanoacrylate

Identifiers

PMID40007976
PMCPMC11850993

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.