Evidence map›Paper›PMID 40007941›Full record

ArticleTherapeutic advances in infectious disease

Treatment response of patients with tuberculosis and HIV co-infection: a retrospective analysis of secondary data from Shanghai, China, 2010-2020.

Chenyu Dong, Renfang Zhang, Shenyang Li, Jun Chen, Yunhe Liu, Xiaoqiong Xia, Gang Liu, Yinzhong Shen, Lei Liu, Liyan Zeng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chenyu DongInstitutes of Biomedical Sciences, Intelligent Medicine Institute, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-3993-6300
Renfang ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Shenyang LiShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jun ChenShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yunhe LiuInstitutes of Biomedical Sciences, Intelligent Medicine Institute, Fudan University, Shanghai, China.
Xiaoqiong XiaInstitutes of Biomedical Sciences, Intelligent Medicine Institute, Fudan University, Shanghai, China.
Gang LiuInstitutes of Biomedical Sciences, Intelligent Medicine Institute, Fudan University, Shanghai, China.
Yinzhong ShenShanghai Public Health Clinical Center, Fudan University, Jinshan District, Shanghai 201508, China.
Lei LiuInstitutes of Biomedical Sciences, Intelligent Medicine Institute, Fudan University, Shanghai 200032, China.
Liyan ZengInstitutes of Biomedical Sciences, Intelligent Medicine Institute, Fudan University, Xuhui District, Shanghai, 200032, China.ORCID https://orcid.org/0000-0003-0376-0833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: At present, there is a need for more substantial real-world evidence on the factors influencing the effectiveness of tuberculosis (TB) treatment in HIV/TB co-infected patients. Objectives: This retrospective study aims to identify factors affecting TB treatment effectiveness in HIV/TB co-infected patients. Design: Retrospective cross-sectional study. Methods: We included 461 HIV/TB co-infected patients, deriving 742 samples based on each initial positive TB test period. A total of 7788 valid treatment records corresponding to 17 TB drug compositions and 150 clinical indicators (each > 100 records) were used for analysis. Data mining techniques were employed, including consensus clustering, Fisher's exact test, stratified analysis, multivariate logistic regression analysis, and three modeling approaches (logistic regression, support vector machine, and random forest). Results: The TB treatment effectiveness of CD4 Conclusion: CD4

Indexed as

clinical indicatorsdrug regimensHIV/TB co-infected patientimmune levelsTB treatment effectivenesstuberculosis

Identifiers

PMID40007941
PMCPMC11851764

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.