ArticleJournal of oral microbiology2025
Preventive effects of
Article in Journal of oral microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Oral probiotic Weissella cibaria improves halitosis and reduces periodontal pathogens: a randomized, double-blind, placebo-controlled trial.BMC oral health · 2026Trial
- Genome-guided characterization ofMicrobiology spectrum · 2026Article
- Combination of Lacticaseibacillus rhamnosus and Weissella confusa treatment improves ligature-induced periodontitis in rats via immune modulation and inhibition of oral pathogens.BMC oral health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Periodontitis is a widespread chronic inflammatory disease impacting 20-50% of the global population. Methods: This study evaluated the effects of Results: The administration of CMU significantly improved gingivitis and plaque indices in a dose-dependent manner. Macroscopic analysis and micro-computed tomography showed a dose-dependent reduction in alveolar bone loss in the CMU groups. Although histopathological analysis indicated a decrease in bone loss, statistical significance was not achieved in the high-dose group. Pro-inflammatory mediators such as TNF-α, IL-6, MMP-1, and MMP-9 were suppressed in a dose-dependent manner in the CMU groups. Additionally, mid- and high-dose CMU increased the relative abundance of Weissella in the oral microbiome. Conclusions: CMU can influence the oral microbiome, reduce inflammatory mediators, and alleviate histological changes in periodontal tissue, highlighting its potential as a probiotic strain for preventing periodontitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.