Evidence map›Paper›PMID 40007928›Full record

ArticleCureus2025

Very Low Internal Echoes With Enhanced Posterior Echoes Suggest the Aggressive Nature of Expanding Ovoid Breast Cancers: A Case Report.

Ayaka Kurumada, Shoji Oura, Mariko Honda

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ayaka KurumadaDepartment of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, JPN.
Shoji OuraDepartment of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, JPN.
Mariko HondaDepartment of Surgery, Izumiotsu Municipal Hospital, Izumiotsu, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 40-year-old woman with a left breast mass was referred to our hospital. Mammography showed only a mass shadow. An ultrasound showed a 30mm oval mass with distinct borders, focal cystic parts, enhanced posterior echoes, and very low internal echoes. Magnetic resonance images showed that the tumor had mixed hypo- and hyper-intense areas both on T1- and fat-suppressed T2-weighted images. In addition, time-signal intensity images showed a washout pattern in the solid part of the tumor. A vacuum-assisted biopsy of the mass showed highly atypical cells growing in a solid fashion. The patient, therefore, underwent breast-conserving surgery and sentinel node biopsy. A post-operative pathological study showed that the tumor had a solid growth pattern, intra-tumoral bleeding, a triple-negative phenotype, a nuclear grade of 3, and a Ki-67 labeling index of 90%. Very low internal echo areas were consistent with the proliferative areas of poorly differentiated cancer cells. In conclusion, tumors should be highly aggressive when they have expanding ovoid shapes, enhanced posterior echoes, and very low internal echoes.

Indexed as

breast cancerenhanced posterior echoeshigh ki-67 labelling indextumor aggressivenessvery low internal echoes

Identifiers

PMID40007928
PMCPMC11857666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.