Evidence map›Paper›PMID 40007925›Full record

ArticleCureus2025

A Case of Anti-LGI1 Limbic Encephalitis Presenting With Non-convulsive Status Epilepticus and Requiring a Long Period of Hospitalization.

Naotaka Miyazawa, Minatani Shinobu, Akitoshi Takeda, Yoshiaki Itoh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Naotaka MiyazawaNeurology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, JPN.
Minatani ShinobuNeurology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, JPN.
Akitoshi TakedaNeurology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, JPN.
Yoshiaki ItohNeurology, Graduate School of Medicine, Osaka Metropolitan University, Osaka, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An 81-year-old man was brought to our hospital with tonic-clonic seizures and a gradual progression of cognitive dysfunction. Four months prior, he experienced transient episodes of stiffness and unresponsiveness. One month later, the patient began to exhibit disorientation to time and place. Upon admission, fluid-attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI) revealed hyperintense lesions in the right limbic cortex. Electroencephalography (EEG) revealed lateralized periodic discharges in the right temporal lobe. Serum anti-LGI1 antibody was detected. Based on these findings, anti-LGI1 limbic encephalitis (LE) was diagnosed. His symptoms improved with corticosteroid treatment; however, six months of hospitalization were necessary for him to regain independence in daily living. Although the prognosis of anti-LGI1 LE is generally favorable, older age at onset, non-convulsive status epilepticus, diffuse limbic lesions, and delayed treatment may have influenced the clinical course in this case.

Indexed as

autoimmune encephalitisfacio-brachial dystonic seizurefocal impaired awareness seizureperiodic dischargesteroid pulse therapy

Identifiers

PMID40007925
PMCPMC11858472

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.