Evidence map›Paper›PMID 40007916›Full record

ArticleCureus2025

Spontaneous Medial Rectus Haematoma: A Sight-Threatening Complication of Warfarin Toxicity.

Sara Sharif, Haider Shah, Paras Agarwal

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sara SharifOphthalmology, University of Liverpool, Liverpool, GBR.
Haider ShahOpthalmology, Arrowe Park Hospital, Birkenhead, GBR.
Paras AgarwalOphthalmology, Warrington Hospital, Warrington and Halton Hospitals NHS Foundation Trust, Warrington, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report highlights a rare instance of spontaneous medial rectus haematoma in a 77-year-old female, attributed to warfarin use, underscoring its clinical significance. The patient initially presented with acute right eye pain, peri-orbital swelling, and reduced vision. Examination revealed a tense globe and elevated intraocular pressure (IOP), prompting emergency lateral canthotomy and inferior cantholysis. However, despite the initial procedure, her IOP remained elevated, indicating direct pressure from the haematoma on the globe and necessitating additional upper and lower eyelid lateral cantholysis. Medical management was also initiated to control the IOP. Over four months, the patient's visual acuity improved significantly, although a relative afferent pupillary defect persisted. This case underscores the rarity of spontaneous medial rectus haematoma in anticoagulated patients and highlights the critical importance of vigilant international normalized ratio (INR) monitoring and timely intervention to reduce morbidity and the risk of vision loss.

Indexed as

canthotomyocular proptosisorbitorbital haemorrhage‏strabismuswarfarin toxicity

Identifiers

PMID40007916
PMCPMC11851350

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.