Evidence map›Paper›PMID 40007877›Full record

ReviewClinical ophthalmology (Auckland, N.Z.)2025

Cystoid Macular Edema Following Rhegmatogenous Retinal Detachment Repair Surgery: Incidence, Pathogenesis, Risk Factors and Treatment.

Enrico Bernardi, Neil Shah, Lorenzo Ferro Desideri, Jelena Potic, Janice Roth, Rodrigo Anguita

Abstract readReview
In one paragraph

Review in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Enrico BernardiDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, CH-3010, Switzerland.ORCID 0000-0002-8082-4813
Neil ShahMoorfields Eye Hospital NHS Foundation Trust, London, UK.
Lorenzo Ferro DesideriDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, CH-3010, Switzerland.
Jelena PoticDepartment of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland.
Janice RothDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, CH-3010, Switzerland.
Rodrigo AnguitaDepartment of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, CH-3010, Switzerland.ORCID 0000-0003-2382-1111

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To review the incidence, risk factors, and treatments for cystoid macular edema (CME) following rhegmatogenous retinal detachment (RRD) repair surgery. Methods: A comprehensive literature search was conducted across multiple databases. Relevant studies published within the last 20 years were selected and reviewed. Results: The incidence of CME following RRD repair ranges from 6% to 36%, with higher rates associated with silicone oil tamponade. Key risk factors include recurrent RRD, pre-existing proliferative vitreoretinopathy, older age, and post-RRD cataract surgery. Treatment options primarily focus on anti-inflammatory approaches, with topical NSAIDs and corticosteroids as first-line treatments. For persistent cases, intravitreal corticosteroid injections, particularly dexamethasone implants, have shown potential. Conclusion: CME remains a significant complication following RRD repair, impacting visual recovery. While various treatment options exist, management of persistent CME remains challenging. Better understanding of the underlying mechanisms of CME is required to develop more effective treatment strategies, particularly for cases resistant to current therapies.

Indexed as

cystoid macular edemaPVRretinal detachmentretinectomyscleral bucklesilicone oilsteroidsvitrectomy

Identifiers

PMID40007877
PMCPMC11853832

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.