ArticleEFSA journal. European Food Safety Authority2016
Safety and efficacy of inositol as nutritional additive for dogs and cats.
Article in EFSA journal. European Food Safety Authority, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Research Note: Jejunum phosphatases and systemic myo-inositol in broiler chickens fed without or with supplemented phytase.Poultry science · 2020Article
- Safety and efficacy of inositol as nutritional additive for dogs and cats.EFSA journal. European Food Safety Authority · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inositol (cyclohexenehexol) is a sugar alcohol synthesised by most plants and animals. It exists in nine possible stereoisomers, four of which are physiologically active. Inositol is an essential micronutrient for salmon, carp, tilapia and shrimps, particularly juveniles. In a previous opinion on inositol, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP6) could not conclude on the safety and efficacy of inositol when used in pet food at the recommended use levels of between 500 and 3,000 mg/kg owing to insufficient evidence. The European Commission requested that the European Food Safety Authority re-evaluate the safety and efficacy of inositol when used as nutritional additive (functional group: vitamins, pro-vitamins and chemically well-defined substances having a similar effect) in food for dogs and cats. In the present application, the applicant proposed a maximum supplementation level of 1,500 mg inositol/kg dry complete feed for dogs and cats. The FEEDAP Panel concluded, based on the free inositol concentrations found in commercial diets for pets, that inositol up to a total content of 3,000 mg free inositol/kg dry complete feed (88% dry matter) could be considered safe for dogs and cats. Evidence is lacking for any benefit of inositol supplementation of foods for dogs and cats.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.