Evidence map›Paper›PMID 40007815›Full record

ArticleClinical, cosmetic and investigational dermatology2025

Successful Treatment of Facial Multiple Melanocytic Nevus-Like Dark Macules Caused by Severe Acne Vulgaris by a Single Session of Intense Pulsed Light Treatment.

Jinxiang Yang, Jinwen Shen, Yuwei Kong, Lei Wang, Zhirong Yao, Jianying Liang, Xia Yu

Abstract readCase Reports
In one paragraph

Article in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinxiang Yang *Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.ORCID 0009-0007-3733-1996
Jinwen Shen *Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Yuwei Kong *Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Lei WangDepartment of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Zhirong YaoDepartment of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Jianying LiangDepartment of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.
Xia YuDepartment of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objective: The case report aims to demonstrate the therapeutic effects of a single session of intense pulsed light (IPL) treatment on facial multiple melanocytic nevus-like dark macules induced by severe acne vulgaris. Materials and Methods: A 17-year-old male with acne was assessed as Pillsbury IV according to the Pillsbury classification. After three sessions of photodynamic therapy (PDT), he experienced an increase in number and darkening of facial melanocytic nevus-like dark macules. We attempted to use broadband light (BBL) (SCITON Company, USA) (420nm, 8J, 180ms; 515nm, 13J, 20ms; 560nm, 16J, 24ms; 590nm, 16J, 24ms) therapy to improve post-inflammatory erythema (PIE) and post-inflammatory hyperpigmentation (PIH). Following a baseline assessment, we performed a single session of IPL treatment on the patient and evaluated the changes in melanocytic nevus-like dark macules, PIE, PIH, and sebum secretion through standardized photography. Results: Compared to the baseline, we observed a significant reduction of the patient's melanocytic nevus-like dark macules and a significant improvement in PIE, PIH, and sebum secretion after a single IPL treatment. Conclusions: This study provides preliminary evidence of the effects of IPL treatment on melanocytic nevi associated with severe acne vulgaris. Further research is warranted to elucidate the underlying mechanisms and promote the wider application of this treatment modality in managing acne sequelae.

Indexed as

acne vulgarisintense pulsed lightmelanocytic nevusphotodynamic therapy

Identifiers

PMID40007815
PMCPMC11853118

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.