Evidence map›Paper›PMID 40007704›Full record

ArticleAnnals of Ibadan postgraduate medicine2024

LEVEL OF MONOCYTE CHEMOATTRACTANT PROTEIN-1 (MCP-1) AND PATTERN OF INJURIES IN POLYTRAUMA PATIENTS.

M Balogun

Abstract read
In one paragraph

Article in Annals of Ibadan postgraduate medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

1 author.

M BalogunDepartment of Surgery, College of Medicine, University of Ibadan and Consultant, Trauma and Orthopaedic Surgeon, University College Hospital, Ibadan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Trauma and trauma-related injuries are rife worldwide and constitutes part of the most common cause of hospital admission. Monocyte Chemoattractant Protein-1 is produced by several array of cells in acute traumatic injury and tissue repair. Materials and Method: This research is a prospective hospital-based study carried out at a tertiary hospital in south western Nigeria. Patients admitted through the Emergency department were categorized based on the inclusion criteria. Those eligible for inclusion were recruited and had their blood samples taken into an endotoxin free test tube at 48 +/- 2 hours after trauma. MCP-1 levels in the serum was estimated though the Human MCP-1 ELISA kit. This process was carried out using the ELISA technique based on the manufacturer's guide. Results: The samples of 110 patients were analyzed, patient with the highest combination of injury had injuries to the Head and Neck, Face, chest, Abdomen, Extremity fractures and skin with MCP-1 value of 463pg/ml. The test of relationship using the F-test (0.299), and P-value (1.000) does not demonstrate any correlation between patterns of injury to MCP-1 values in polytrauma patients. Conclusion: The study showed no significant relationship between the patterns of injury in polytrauma patients with serum MCP-1 levels. Therefore, injury pattern cannot be used to predict MCP-1 levels.

Indexed as

FracturesMCP-1Pattern of injuryPolytrauma

Identifiers

PMID40007704
PMCPMC11848364

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.