Evidence map›Paper›PMID 40007655›Full record

ArticleEndoscopy international open2025

Novel device for blunt dissection in third space endoscopy: Preliminary animal study (with video).

Takashi Yokouchi, Teppei Masunaga, Kurato Miyazaki, Motohiko Kato, Shota Fujii, Kota Momose, Kotaro Yamashita, Takuro Saito, Koji Tanaka, Kazuyoshi Yamamoto and 6 more

Abstract read
In one paragraph

Article in Endoscopy international open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Takashi YokouchiDepartment of Next Generation Endoscopic Intervention (Project ENGINE), Osaka University School of Medicine Graduate School of Medicine, Suita, Japan.ORCID 0009-0003-2901-4596
Teppei MasunagaDivision of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Shinjuku-ku, Japan.ORCID 0000-0002-3968-0969
Kurato MiyazakiDivision of Research and Development for Minimally Invasive Treatment, Cancer Center, Keio University School of Medicine, Shinjuku-ku, Japan.
Motohiko KatoCenter for Diagnostic and Therapeutic Endoscopy, Keio University School of Medicine, Tokyo, Japan.ORCID 0000-0002-7579-1316
Shota FujiiSanyo Co Ltd, Tondabayashi, Japan.
Kota MomoseDepartment of Next Generation Endoscopic Intervention (Project ENGINE), Osaka University School of Medicine Graduate School of Medicine, Suita, Japan.
Kotaro YamashitaDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Takuro SaitoDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Koji TanakaDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Kazuyoshi YamamotoDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Tomoki MakinoDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Tsuyoshi TakahashiDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Yukinori KurokawaDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Hidetoshi EguchiDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Yuichiro DokiDepartment of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, Japan.
Kiyokazu NakajimaDepartment of Next Generation Endoscopic Intervention (Project ENGINE), Osaka University School of Medicine Graduate School of Medicine, Suita, Japan.ORCID 0000-0001-8635-7585

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and study aims: Blunt dissection is not commonly performed in flexible endoscopic procedures. We developed a novel blunt dissection device and evaluated its feasibility, safety, and potential effectiveness in third space endoscopy procedures. Materials and methods: The device consists of a cotton swab and a flexible shaft. To evaluate its functionality, creation of 4-cm submucosal tunnels in live swine stomachs was attempted by either blunt dissection using our device or sharp dissection using a standard monopolar knife. Data on factors such as completion rate, operating time, adverse events, necessity of submucosal injection, and dissected submucosal thickness were collected. Results: Eighteen submucosal tunnels were successfully created (sharp: 9, blunt: 9) by two experienced endoscopists and one novice endoscopist. Median operating time was significantly shorter in the blunt dissection group (239 vs. 429 s, Conclusions: Blunt dissection using our device was feasible, safe, and potentially effective in third space endoscopy procedures by shortening operating time, reducing submucosal injections, and potentially minimizing muscle layer injury.

Indexed as

Endoscopic resection (ESD, EMRc, ...)Endoscopic resection (polypectomy, ESD, EMRc, ...)Endoscopy Lower GI TractEndoscopy Upper GI TractPOEM

Identifiers

PMID40007655
PMCPMC11855248

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.