Evidence map›Paper›PMID 40007591›Full record

ArticleFrontiers in medicine2025

Associations between asthma and Life's Essential 8: a cross-sectional study.

Jiao Xu, Jianlei Tang

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Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jiao XuDepartment of Respiratory and Critical Care Medicine, WuJin Hospital Affiliated with Jiangsu University, WuJin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China.
Jianlei TangRehabilitation Department, WuJin Hospital Affiliated with Jiangsu University, WuJin Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Asthma is a serious respiratory disease attributed to multiple factors. The Life's Essential 8 (LE8), introduced by the American Heart Association, aims to improve and maintain cardiovascular health. However, the correlation between LE8 components and asthma remains unclear. We hypothesized that LE8 is a protective factor against asthma. Materials and methods: Multiple logistic regression analysis, restricted cubic spline (RCS) analysis, and subgroup analysis were used to analyze the data collected from the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2018. Results: A total of 3,360 participants with asthma were included in the analysis. With all confounders controlled for, LE8 scores were negatively correlated with asthma prevalence (odds ratio (OR) per 10-point increment, 0.85 [95% confidence interval (CI), 0.82-0.88]). Compared to low LE8 scores, moderate and high LE8 scores were associated with reduced asthma risk, with adjusted ORs (95% CIs) of 0.59 (0.51-0.68) and 0.48 (0.39-0.58), respectively. Non-linear correlations were observed between LE8 scores and asthma ( Conclusion: Asthma is associated with components of LE8, which warrants further attention and may contribute to reducing asthma prevalence.

Indexed as

asthmahealth behaviors scorehealth factors scoreLife’s Essential 8odd ratios

Identifiers

PMID40007591
PMCPMC11851080

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.