Evidence map›Paper›PMID 40007538›Full record

ArticleFrontiers in immunology2025

A hyper-acute immune hemolytic anemia induced by contrast medium was successfully treated with eculizumab: a case report.

Sabine Hermann, Karina Althaus, Migdat Mustafi, Beate Mayer, Peter Rosenberger, Helene Anna Haeberle, Alice Bernard

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sabine HermannDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, Germany.
Karina AlthausClinical and Experimental Transfusion Medicine, University Hospital Tuebingen, Tuebingen, Germany.
Migdat MustafiDepartment of Thoracic and Vascular Surgery, University Hospital Saarland, Saarbruecken, Germany.
Beate MayerInsitutition of Transfusion Medicine, Charité, Berlin, Germany.
Peter RosenbergerDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, Germany.
Helene Anna HaeberleDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, Germany.
Alice BernardDepartment of Anaestesiology and Intensive Care Medicine, University Hospital Tuebingen, Tuebingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast medium is frequently associated with allergic reactions and kidney dysfunction. However, contrast media can induce hemolytic anemia with a broad spectrum of hemolytic manifestations. We report a 38-year-old patient with very severe immune hemolytic anemia after the application of iomeprol due to a CT of the thorax/abdomen. In this case report, we illustrate the diagnostics and treatment of life-threatening hemolytic anemia induced by a contrast medium that was successfully treated with eculizumab.

Indexed as

Anemia, HemolyticAnemia, Hemolytic, AutoimmuneAntibodies, Monoclonal, HumanizedComplement Inactivating AgentsContrast MediaAdultHumansMaleTomography, X-Ray ComputedTreatment OutcomeAntibodies, Monoclonal, HumanizedComplement Inactivating AgentsContrast Mediaeculizumabcontrast medium-induced hemolysisdrug-induced hemolysiseculizumabhemolytic anemiaimmunological hemolysis

Identifiers

PMID40007538
PMCPMC11850351

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.