ArticleAsia-Pacific journal of oncology nursing2025
Describing the minimally clinically important difference of a chemotherapy-induced peripheral neuropathy patient-reported outcome measure in young adults.
Article in Asia-Pacific journal of oncology nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Musculoskeletal Ultrasound and MRI in the Evaluation of Chemotherapy-Induced Peripheral Neuropathy: A Review.Medical science monitor : international medical journal of experimental and clinical research · 2026Review
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Authors and funding
9 authors.
Funding
Abstract
Objective: The purpose of this secondary analysis was to characterize the reliability, validity, and minimally clinically important difference (MCID) of change scores over time of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-CIPN-20 item (QLQ-CIPN20) in young adults receiving paclitaxel or vincristine. Methods: Fifty young adults receiving vincristine or paclitaxel for the treatment of cancer completed the QLQ-CIPN20 at three time points associated with increasing cumulative chemotherapy dose. The Subject Significance Questionnaire was completed at T3. The analyses were focused on the calculation of floor and ceiling effects, internal consistency reliability, longitudinal validity, construct validity, and the MCID using an anchor-based approach for the QLQ-CIPN20 sensory and motor subscales. Results: By T3, 50% and 52% of participants reported QLQ-CIPN20 sensory and motor subscale scores at the floor, respectively. The internal consistency reliability of the sensory ( Conclusions: Study results provided preliminary evidence surrounding the MCID for worsening of QLQ-CIPN20 scores using an anchor based on young adults' perceived change in CIPN severity. Further research is needed to develop psychometrically sound CIPN patient-reported outcome measures to effectively evaluate the impact of CIPN interventions among young adults.
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Registered trials
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