ArticleJournal of Parkinson's disease2025
A framework to standardize gait study protocols in Parkinson's disease.
Article in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Determining Falls Risk in People with Parkinson's Disease Using Wearable Sensors: A Systematic Review.Sensors (Basel, Switzerland) · 2025Pooled it
- Lessons Learned From a Delayed-Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease.Annals of clinical and translational neurology · 2026Trial
- Construct validity of instrumented gait assessments in hospital and daily life mobility in patients with Parkinson's disease and atypical Parkinson's syndromes: an exploratory study.Journal of neurology · 2026Trial
- Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease.Annals of clinical and translational neurology · 2026Article
- Step-by-step insight into gait analysis: A narrative review unlocking knee biomechanics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Review
- Walking as a Window to the Brain: Redefining Gait in Neurology.Medical sciences (Basel, Switzerland) · 2026Review
- Deep learning for freezing of gait assessment using inertial measurement units: a multicentre validation study.NPJ Parkinson's disease · 2026Article
- Spatio-temporal gait signatures across prodromal and early Parkinson's disease in two independent cohorts.Scientific reports · 2026Article
- What is new in Freezing of Gait?Journal of neurology · 2026Review
- An updated definition of freezing of gait.Nature reviews. Neurology · 2026Review
- The future of clinical trials? Monitoring mobility as an outcome measure in Parkinson's disease: The mobilise-D study.Journal of Parkinson's disease · 2026Article
- Clinical utility of digital technologies in Parkinson's disease.Journal of neural transmission (Vienna, Austria : 1996) · 2026Review
- Longitudinal characterization of biomechanical alterations in a Parkinson's disease mouse model using three-dimensional ground reaction forces.Clinical parkinsonism & related disorders · 2026Article
- Beyond protocol standardization: The importance of data curation and software transparency.Journal of Parkinson's disease · 2025Article
- Multidimensional factors of health-related quality of life in parkinson's disease using ensemble learning and network analysis.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
20 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BackgroundResearch over the past twenty years has shown that gait outcomes have a high sensitivity for diagnosing Parkinson's disease (PD), for detecting the effects of interventions, and for monitoring disease progression, even in early disease. However, the lack of standardization in protocols and reported gait measures is impeding data aggregation across study sites and contributes to heterogeneity in the results, thus limiting the adoption of gait outcomes in clinical trials.ObjectiveTo provide recommendations for a minimum set of gait measures to be adopted in projects evaluating people with PD to enhance standardization across the field.MethodsThe Gait Advisors Leading Outcomes for Parkinson's (GALOP) committee is an advisory committee for the MJFF. Based on a five-step approach, GALOP generated recommendations for standardizing protocols that assess quantitative gait measures, following expert consensus on best practices.ResultsBuilt on the literature and consensus amongst experts, we recommend a minimum set of meta-data to accompany gait protocols and a minimum gait assessment protocol to be performed at a comfortable speed. Suggestions on challenging testing are provided.ConclusionsTo support and empower the scientific community, we have generated recommendations to collect and share gait data gathered from people with PD using an open data repository. Standardizing gait protocols and outcomes in PD has the potential of accelerating research and clinical trials, harmonizing protocols across study sites, fostering collaborations, and in the long run, improving patient care and quality of life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.