Evidence map›Paper›PMID 40007019›Full record

ArticleViruses2025

Epidemiological Study and Genetic Diversity Assessment of Porcine Epidemic Diarrhea Virus (PEDV) in Yunnan Province, China.

Pei Zhu, Hong Yuan, Xianghua Shu, Xue Li, Yaoxing Cui, Lin Gao, Rui Yan, Taoying Yu, Chunlian Song, Jun Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pei ZhuYunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming 650224, China.ORCID 0000-0002-6784-8386
Hong YuanCollege of Animal Medicine, Yunnan Agricultural University, Kunming 650201, China.
Xianghua ShuCollege of Animal Medicine, Yunnan Agricultural University, Kunming 650201, China.
Xue LiCollege of Animal Medicine, Yunnan Agricultural University, Kunming 650201, China.
Yaoxing CuiCollege of Animal Medicine, Yunnan Agricultural University, Kunming 650201, China.
Lin GaoYunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming 650224, China.
Rui YanMenglian County Animal Disease Prevention and Control Center, Menglian 665899, China.
Taoying YuGongshan County Animal Disease Prevention and Control Center, Gongshan 673599, China.
Chunlian SongCollege of Animal Medicine, Yunnan Agricultural University, Kunming 650201, China.
Jun YaoYunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming 650224, China.

Funding

Key Research and Development Plan of Yunnan Province Science and Technology Department 202303AK140031the Innovation Guidance and Technology-Based Enterprise Cultivation Program of Yunnan Province Science and Technology Department 202304BI090003the Major Science and Technology Project of Yunnan Province 202202AE090027
6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) is a highly contagious pathogen responsible for devastating enteric disease and lethal watery diarrhea, leading to significant economic losses in the global swine industry. Understanding the epidemiology and genetic diversity of PEDV over the past decade is crucial for the effective prevention and treatment of porcine epidemic diarrhea. In this study, 1851 fecal samples were collected from pigs exhibiting diarrhea symptoms across 11 cities in Yunnan Province between 2013 and 2022. The prevalence of PEDV, along with other common swine diarrhea viruses, including porcine transmissible gastroenteritis virus (TGEV), porcine rotavirus (PoRV), porcine Sapporo virus (PoSaV), porcine stellate virus (PaStV), and porcine delta coronavirus (PDCoV) was assessed using a polymerase chain reaction (PCR) assay. The results revealed a total detection rate of 52.94% (980/1851) for the six viruses, with PEDV accounting for 25.93% (480/1851) of cases. Further analysis showed that weaned piglets were more susceptible to PEDV than fattening pigs, with the highest prevalence observed in spring (61.52%, 275/447) and the lowest in summer (12.68%, 97/765). Dual infections were also identified, with PEDV + PoSaV being the most common combination (2.81%, 52/1851), followed by PEDV + PoRV, with a detection rate of 1.67% (31/1851). Phylogenetic analysis of the PEDV S genes revealed that the 28 epidemic strains in Yunnan Province shared a nucleotide sequence homology from 91.4% to 98.4% and an amino acid sequence homology ranging from 85.6% to 99.3%. All strains were classified as GII variant strains. This study provides a comprehensive overview of the epidemiology of PEDV and its co-infection patterns with other common diarrhea-causing viruses in the swine herds of Yunnan Province over the past decade. These findings offer valuable insights for the development of effective prevention and control strategies to mitigate the impact of PEDV and other enteroviruses on the swine industry in Yunnan Province.

Indexed as

Coronavirus InfectionsGenetic VariationPorcine epidemic diarrhea virusSwine DiseasesAnimalsChinaDiarrheaFecesPhylogenyPrevalenceSwineco-infectiondiarrhea-causing virusesepidemiologygenetic diversityPEDV

Identifiers

PMID40007019
PMCPMC11861340

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.