Evidence map›Paper›PMID 40006978›Full record

ArticleViruses2025

Multi-Province Outbreak of Acute Gastroenteritis Linked to Potential Novel Lineage of GII.17 Norovirus in Argentina in 2024.

Karina A Gomes, Juan I Degiuseppe, Paula M Morón, Karina A Rivero, Christian Barrios Matthieur, Carolina Paladino, Facundo G Cuba, María S Haim, Tomás J Poklépovich Caride, Juan A Stupka

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Global trends in norovirus genotype distribution among medically attended children with acute gastroenteritis, 2020-2025.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2026
    Article
  2. Article
  3. Wastewater-based surveillance of norovirus GI and GII: Comparative performance of commercial and in-house RT-qPCR Assays.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karina A GomesLaboratory of Viral Gastroenteritis-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.
Juan I DegiuseppeLaboratory of Viral Gastroenteritis-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.ORCID 0000-0002-2181-7795
Paula M MorónLaboratory of Viral Gastroenteritis-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.
Karina A RiveroLaboratory of Viral Gastroenteritis-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.
Christian Barrios MatthieurLaboratory of Viral Gastroenteritis-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.
Carolina PaladinoNational Center of Genomics and Bioinformatics-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.
Facundo G CubaNational Center of Genomics and Bioinformatics-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.ORCID 0009-0008-3172-0330
María S HaimNational Center of Genomics and Bioinformatics-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.ORCID 0000-0002-0118-1996
Tomás J Poklépovich CarideNational Center of Genomics and Bioinformatics-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.ORCID 0000-0002-0384-6066
Juan A StupkaLaboratory of Viral Gastroenteritis-ANLIS "Dr. Carlos G. Malbrán", Ciudad Autónoma de Buenos Aires 1281, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noroviruses represent one of the leading causes of outbreaks and sporadic acute gastroenteritis (AGE) cases across all age groups. Although the GII.4 norovirus has been identified as the primary cause of most AGE outbreaks, the transient predominance of other genotypes has been reported globally. In this study, we describe a multi-province AGE outbreak caused by a potential new lineage of norovirus GII.17[P17], which has been recently detected at a high incidence in the United States and Europe. An amino acid analysis of the major viral capsid protein revealed several substitutions in the hypervariable region compared to strains circulating in the mid-2010s, which could play a key role in immune evasion. This is the first report of the detection of these viruses in the Southern Hemisphere, underscoring the importance of maintaining active genomic surveillance in the context of increasing numbers of acute gastroenteritis outbreaks.

Indexed as

Caliciviridae InfectionsDisease OutbreaksGastroenteritisNorovirusAdolescentAdultAgedArgentinaCapsid ProteinsChildChild, PreschoolFemaleGenotypeHumansInfantMaleCapsid Proteinsgastroenteritisnorovirus GII.17outbreak

Identifiers

PMID40006978
PMCPMC11860177

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.