Evidence map›Paper›PMID 40006970›Full record

ArticleViruses2025

Effectiveness and Immunogenicity of the MMR Vaccine Against SARS-CoV-2 Among Healthcare Workers.

Hyeri Seok, Joon-Yong Bae, Jooyun Kim, Won Suk Choi, Heedo Park, Jungmin Lee, Sohyun Lee, Chulwoo Kim, Man-Seong Park, Dae Won Park

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hyeri SeokDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.ORCID 0000-0002-2032-9538
Joon-Yong BaeDepartment of Microbiology, Institute for Viral Diseases, Vaccine Innovation Center, Korea University Medicine, Seoul 02841, Republic of Korea.ORCID 0000-0002-2483-4208
Jooyun KimDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.
Won Suk ChoiDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.
Heedo ParkDepartment of Microbiology, Institute for Viral Diseases, Vaccine Innovation Center, Korea University Medicine, Seoul 02841, Republic of Korea.
Jungmin LeeDepartment of Microbiology, Institute for Viral Diseases, Vaccine Innovation Center, Korea University Medicine, Seoul 02841, Republic of Korea.ORCID 0000-0002-7952-2877
Sohyun LeeDepartment of Microbiology, Institute for Viral Diseases, Vaccine Innovation Center, Korea University Medicine, Seoul 02841, Republic of Korea.ORCID 0000-0002-3453-1075
Chulwoo KimDepartment of Microbiology, Institute for Viral Diseases, Vaccine Innovation Center, Korea University Medicine, Seoul 02841, Republic of Korea.
Man-Seong ParkDepartment of Microbiology, Institute for Viral Diseases, Vaccine Innovation Center, Korea University Medicine, Seoul 02841, Republic of Korea.
Dae Won ParkDivision of Infectious Diseases, Department of Internal Medicine, Korea University Ansan Hospital, Ansan 15355, Republic of Korea.

Funding

Korea Basic Science Institute 2021R1A6C101C570National Research Foundation of Korea NRF-2022M3A9I2017241
6 · The paper itself

Abstract

The purpose of this study was to evaluate the effectiveness and immunogenicity of the measles-mumps-rubella (MMR) vaccine against SARS-CoV-2 in healthcare workers at one medical institution. The effectiveness of the MMR vaccine against SARS-CoV-2 was evaluated in overall healthcare workers (HCWs). In addition, neutralizing antibodies to SARS-CoV-2 were measured according to the subjects' measles immunity status with serum samples collected before the coronavirus disease 2019 pandemic period. The effectiveness of the MMR vaccine for SARS-CoV-2 in all HCWs and measles IgG-positive subjects was 34% (adjusted odds ratio [aOR] = 1.20, 95% confidence interval [CI] = 0.53-2.70) and 34% (aOR = 0.66, CI = 0.38-18.4), respectively. The neutralizing antibody levels for SARS-CoV-2 were low in all groups regardless of the measles immune status. The MMR vaccine alone may not provide sufficient protection against SARS-CoV-2.

Indexed as

COVID-19Health PersonnelImmunogenicity, VaccineMeasles-Mumps-Rubella VaccineSARS-CoV-2AdultAntibodies, NeutralizingAntibodies, ViralFemaleHumansImmunoglobulin GMaleMiddle AgedVaccine EfficacyYoung AdultAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GMeasles-Mumps-Rubella VaccineCOVID-19measles–mumps–rubella vaccineSARS-CoV-2vaccine effectivenessvaccine immunogenicity

Identifiers

PMID40006970
PMCPMC11860525

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.