Evidence map›Paper›PMID 40006969›Full record

ReviewViruses2025

Tobacco Mosaic Virus Movement: From Capsid Disassembly to Transport Through Plasmodesmata.

Amr Ibrahim, Nobumitsu Sasaki, James E Schoelz, Richard S Nelson

Abstract readReview
In one paragraph

Review in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amr IbrahimDepartment of Nucleic Acid and Protein Structure, Agricultural Genetic Engineering Research Institute, Agricultural Research Center, Giza 12619, Egypt.ORCID 0000-0003-2392-7303
Nobumitsu SasakiGraduate School of Agriculture, Tokyo University of Agriculture and Technology (TUAT), Fuchu 183-8509, Japan.ORCID 0000-0001-9202-5149
James E SchoelzDivision of Plant Science and Technology, University of Missouri, Columbia, MO 65211, USA.
Richard S NelsonIndependent Researcher, McKinney, TX 75071, USA.ORCID 0000-0003-2086-6998

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Determining mechanisms to establish an initial infection and form intracellular complexes for accumulation and movement of RNA plant viruses are important areas of study in plant virology. The impact of these findings on the basic understanding of plant molecular virology and its application in agriculture is significant. Studies with tobacco mosaic virus (TMV) and related tobamoviruses often provide important foundational knowledge for studies involving other viruses. Topics discussed here include capsid disassembly, establishment of a virus replication complex (VRC), and transport of the VRCs or virus components within the cell to locations at the plasmodesmata for intercellular virus RNA (vRNA) movement. Seminal findings with TMV and related tobamoviruses include detecting co-translational disassembly of the vRNA from the virus rod, full sequencing of genomic vRNA and production of infectious transcript for genetic studies determining virus components necessary for intercellular movement, and biochemical and cell biological studies determining the host factors, protein and membrane, needed for replication and movement. This review highlights many of the studies through the years on TMV and selected tobamoviruses that have impacted not only our understanding of tobamovirus accumulation and movement but also that of other plant viruses.

Indexed as

CapsidPlasmodesmataTobacco Mosaic VirusBiological TransportNicotianaPlant DiseasesRNA, ViralTobamovirusVirus ReplicationRNA, Viralendoplasmic reticulummicrofilamentsmicrotubulesmovement proteinplant-virus interactionplasmodesmatatobacco mosaic virustobamovirusesvacuolevirus movementvirus replication

Identifiers

PMID40006969
PMCPMC11861069

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.