Evidence map›Paper›PMID 40006959›Full record

SynthesisViruses2025

Genetic Diversity and Spatiotemporal Distribution of SARS-CoV-2 Variants in Guinea: A Meta-Analysis of Sequence Data (2020-2023).

Thibaut Armel Chérif Gnimadi, Kadio Jean-Jacques Olivier Kadio, Mano Joseph Mathew, Haby Diallo, Abdoul Karim Soumah, Alpha Kabiné Keita, Castro Gbêmêmali Hounmenou, Nicolas Fernandez-Nuñez, Nicole Vidal, Emilande Guichet and 5 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Thibaut Armel Chérif GnimadiCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.ORCID 0000-0001-5129-2873
Kadio Jean-Jacques Olivier KadioCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.ORCID 0000-0003-4477-1336
Mano Joseph MathewEFREI Research Lab, Panthéon Assas University, 30-32 Avenue de la République, 94800 Villejuif, France.ORCID 0000-0002-4930-6903
Haby DialloCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.ORCID 0009-0006-6324-6157
Abdoul Karim SoumahCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.
Alpha Kabiné KeitaCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.ORCID 0009-0003-9206-9995
Castro Gbêmêmali HounmenouCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.ORCID 0000-0002-2306-6083
Nicolas Fernandez-NuñezInstitut de Recherche pour le Développement (IRD), INSERM, TransVIHMI, University of Montpellier, 34394 Montpellier, France.ORCID 0000-0001-8490-3714
Nicole VidalInstitut de Recherche pour le Développement (IRD), INSERM, TransVIHMI, University of Montpellier, 34394 Montpellier, France.ORCID 0000-0001-7022-2643
Emilande GuichetInstitut de Recherche pour le Développement (IRD), INSERM, TransVIHMI, University of Montpellier, 34394 Montpellier, France.ORCID 0000-0003-0380-2044
Ahidjo AyoubaInstitut de Recherche pour le Développement (IRD), INSERM, TransVIHMI, University of Montpellier, 34394 Montpellier, France.ORCID 0000-0002-5081-1632
Eric DelaporteInstitut de Recherche pour le Développement (IRD), INSERM, TransVIHMI, University of Montpellier, 34394 Montpellier, France.
Martine PeetersInstitut de Recherche pour le Développement (IRD), INSERM, TransVIHMI, University of Montpellier, 34394 Montpellier, France.
Abdoulaye TouréCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.ORCID 0000-0003-2269-6611
Alpha Kabinet KeitaCentre de Recherche et de Formation en Infectiologie de Guinée (CERFIG), Université Gamal Abder Nasser de Conakry, Conakry 6629, Guinea.

Funding

Agence française de développement CZZ3209
6 · The paper itself

Abstract

In Guinea, genomic surveillance has been established to generate sequences of and to identify locally circulating SARS-CoV-2 variants. This study aims to describe the distributions, genetic diversity, and origins of SARS-CoV-2 lineages circulating in Guinea during the COVID-19 pandemic. A migration analysis was performed by selecting all sequences generated in Guinea for variants of concern and interest. From March 2020 to December 2023, 1038 sequences were generated in Guinea and submitted to the Global Initiative on Sharing All Influenza Data (GISAID) database. Of these, 73.1% corresponded to SARS-CoV-2 variants of concern, which were further grouped into Omicron (69.4%), Delta (21.9%), Alpha (6.6%), and Eta (2.1%). Other variants accounted for 26.9% of the total. Among the total variants analyzed, 75 importations into Guinea from various countries worldwide were identified. Most of the importations (40%) originated from African countries, followed in significance by those from European countries (25.3%) and Asia (18.6%). A significant migratory flow was observed within Guinea. The genomic surveillance reported in this study revealed the diversity of SARS-CoV-2 variants circulating in Guinea, emphasizing the importance of large-scale sequencing analyses in understanding the dynamics of the pandemic.

Indexed as

COVID-19Genetic VariationSARS-CoV-2Genome, ViralGuineaHumansPandemicsPhylogenySpatio-Temporal Analysisgenetic diversityguineaphylodynamicSARS-CoV-2

Identifiers

PMID40006959
PMCPMC11860642

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.